ID A0A1R1S9Z0_9ACTN Unreviewed; 1163 AA.
AC A0A1R1S9Z0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:OMI35156.1};
GN ORFNames=SPAR_32826 {ECO:0000313|EMBL:OMI35156.1};
OS Streptomyces sparsogenes DSM 40356.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1331668 {ECO:0000313|EMBL:OMI35156.1, ECO:0000313|Proteomes:UP000186168};
RN [1] {ECO:0000313|EMBL:OMI35156.1, ECO:0000313|Proteomes:UP000186168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40356 {ECO:0000313|EMBL:OMI35156.1,
RC ECO:0000313|Proteomes:UP000186168};
RA Coyne S., Seebeck F.P.;
RT "Genome sequence of Streptomyces sparsogenes DSM 40356.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMI35156.1}.
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DR EMBL; ASQP01000412; OMI35156.1; -; Genomic_DNA.
DR RefSeq; WP_076971801.1; NZ_ASQP01000412.1.
DR AlphaFoldDB; A0A1R1S9Z0; -.
DR Proteomes; UP000186168; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF18563; TubC_N; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186168}.
FT DOMAIN 1044..1119
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 643..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1163 AA; 126718 MW; 1EB085E1F67CF64A CRC64;
MNVTSLLERL LGQGVRITAH GDRLAVSAPE GALSDELKET IRANRDGILQ FLRESEEEAA
RRAVRIEPVD RGAPIPASYA QQRLWLVEQT ATDLPVYNMY FALELRGDLD IGALRGAAQD
LVDRHEILRT ALVETGSGLV QDIRDRCPAV FVEHQAGPDT HDDVMFSIVA TRFQLSSAPL
IRFDLVRAGD SRWTFVVTQH HVVSDGWSTG ILKKELSELY TARVEGRRPR LPELSVQYAD
YAVWEREWLE GELAERQRDH WRHALADLPP LLELVPSRRR ETIQSYRGSA LTFRYDIDLL
ARARRLCSDT GNTLYAVLIA AYSLLLSRMT REDDIAVGSP LANRPYPALE KTPGLFFNSI
TIRTRIDERQ TVREFLAAVR RTTFEAFANQ DLPFDQVVRA VAPERSSSHS PVFQNIFILQ
TYPGERLTLP GVDVAPAPTP FYSAQYDLMF KLREDEDGLD GLLVHNDALL DGDDARRVVD
CFRRLVDHMC ATPDAPLADL SLMDPESTDL VERWNARTRR PVPPEPVHER ILRRLAEDPT
TPALTFRGRS LTRGELAGQA GAVAAGLRAA GLRPGQRVGV MVPRSAELVA VLLGIMSAGM
VYVPLDGAAP RARVDAMLES AECAALVLGD AYAHRCPDFA GPRLPAPDPT RTAVGTGRPT
TAHAGRPTAP EDSAYTVFTS GSTGRPKGVE VTHRNLANLF IALDEAVPLP PEPVWLAVTA
VTFDIAVVEL LWTLARGVRV VLAESSESLR LMTRAEGQPE PLGVPELILT EGVTALQATP
TMLRGVLGLP DGARALARLE LLMVGGEALD HTLARSLKDL GIPRVLNMYG PTETTVWSTC
WEVPADPPER ILVGKPLANT AAHVVDARLN PVPVGMYGEL VLAGAGVARG YAGSPDLTGE
RFPALPALCG QGRAYRTGDV ARRLPSGDLE LLGRIDNQVK VNGYRIELEE IERALNSLPG
VAESAVAVQR EEGRAALVAH CVPRPGAVLD ETALRGALAA LLPDQMLPAA FATAAALPTT
SSGKIDRRAL PPVPLGGVEQ VVTEPANDTE KRLLEVWREV LGSDAVGPAD DFFRSGGTSI
LVAHLLTKVR ERVDADARIV DLFRYPSVQA YAAHMSGRAD PAAPSGHPRT ADPRGRHAAR
LQRRQQVARK QRLRAAEGAA DSD
//
