ID   A0A1R1SIG0_9ACTN        Unreviewed;       374 AA.
AC   A0A1R1SIG0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Helix-turn-helix domain-containing protein {ECO:0000313|EMBL:OMI38026.1};
GN   ORFNames=SPAR_18198 {ECO:0000313|EMBL:OMI38026.1};
OS   Streptomyces sparsogenes DSM 40356.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1331668 {ECO:0000313|EMBL:OMI38026.1, ECO:0000313|Proteomes:UP000186168};
RN   [1] {ECO:0000313|EMBL:OMI38026.1, ECO:0000313|Proteomes:UP000186168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40356 {ECO:0000313|EMBL:OMI38026.1,
RC   ECO:0000313|Proteomes:UP000186168};
RA   Coyne S., Seebeck F.P.;
RT   "Genome sequence of Streptomyces sparsogenes DSM 40356.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMI38026.1}.
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DR   EMBL; ASQP01000252; OMI38026.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R1SIG0; -.
DR   STRING; 67365.GCA_001704635_03883; -.
DR   Proteomes; UP000186168; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186168}.
FT   DOMAIN          1..46
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
SQ   SEQUENCE   374 AA;  40391 MW;  F9065E59CDD62463 CRC64;
     MSQTKLARLM KISLSYLSKI ETGLRPATPP LVAAAASALR VTTARIYGDP FADPSTQHEL
     MNDLRAVVRR HTLPREDVPP PDELAASLKR AAQLRAETDY LSLLKLLPTL LGQATATAMA
     SGGDATAWGQ VADVYSCAYA VAHRFRQPDL ADMIVARQTW AAQQTWNPSA EAAAAWNEAG
     TYQSAGEYAD GLAIVERAIV RYESAPGDGL EHVVHLGSLH LRGVVLASRH EDAKATADHV
     RRAKALAERI KGPDLLQHNL TFGPGNTALY ELAAQIELNA PDKAAEVAGP LLKEPPAGLK
     PSRVGRLAID AARARLATKD LTGAEDALKY AFRVAPQMAE IHPMAREVLR VLWTMHQRSR
     PDLLLMAKRA GLAD
//