ID A0A1R1X4W4_9FUNG Unreviewed; 846 AA.
AC A0A1R1X4W4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Heat shock protein 78, mitochondrial {ECO:0000313|EMBL:OMJ09675.1};
GN ORFNames=AYI70_g10794 {ECO:0000313|EMBL:OMJ09675.1};
OS Smittium culicis.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133412 {ECO:0000313|EMBL:OMJ09675.1, ECO:0000313|Proteomes:UP000187283};
RN [1] {ECO:0000313|EMBL:OMJ09675.1, ECO:0000313|Proteomes:UP000187283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSMNP {ECO:0000313|EMBL:OMJ09675.1,
RC ECO:0000313|Proteomes:UP000187283};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ09675.1}.
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DR EMBL; LSSN01005350; OMJ09675.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1X4W4; -.
DR STRING; 133412.A0A1R1X4W4; -.
DR Proteomes; UP000187283; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000187283};
KW Stress response {ECO:0000313|EMBL:OMJ09675.1}.
FT DOMAIN 146..290
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 559..705
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 745..839
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 412..439
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 846 AA; 94065 MW; CEF5309661E1E6F7 CRC64;
MLSSLKTNRR GFLAPLVNIK GAYLPSLYKP VSFSTASLKT DKLSQFNKSS LLKGFQYQIN
HNLRRYSSFT STNIKPLKYL NLISHKQIRS YAVGNEGLRM GPKKTGEALA LYGVDLTQLA
HDGKLDPVIG RDEEIRRAIQ VLSRRTKNNP VLIGEAGVGK TAIAEGLAQR IVKGEVPESM
KGKKLIALDL GALVAGAKYR GEFEERLKSV LADVTNDQNT ILFIDEMHML LGLGKVDGAM
DAGNLLKPAL ARGMLRCLGA TTVEEYRMNI EKDKALERRF QPIMIDEPSV EDTISILRGL
KEKYEVFHGV SIADSALVSA AVLSNRYVQA RFLPDKAIDL VDEACSKLRT QQESKPESIE
VLERSILTLK IELESLKKET DPASNKRREE IASKIEENSK LCDQLIKQWE VEKENINKIN
EIKKKIDESR KELEAAQRSG NLMKASELQY GIIPDLEKQL PNEQESLTET YAGADDNSSS
ENFGGKSLLN MRVTSEDIAK VVSSSTGIPV NSLVSSEKKK LLNLESILSK RVIGQSQAIE
SISEAIRLSR SGLQSEKRPL GSFMFLGPTG VGKTELCKAI AEFLFSSESN IIRIDMSEYM
EKFSISRLIG APPGYVGYDQ GGELTDAVRK KPYSVILLDE IEKAHHDVTN LLLQVLDEGH
LTDSQGRTVD FRNTIVIMTS NLGAELIAED SSSRFTINEV HDKVDNFDES AVSEKTKATI
LNLVKHHFSP EFTNRVDEVL VFNRLSLPMI RKIVDIRLAE LDKKLESQNI SLDVTDSAKE
WLSVNGYDPV FGARPLNRLI QKKIMNRLAK MIIDGQIMSG SNVKVDTTES TVDEKTVEIL
SIEPSS
//
