ID A0A1R1XR30_9FUNG Unreviewed; 1213 AA.
AC A0A1R1XR30;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Calcium-activated potassium channel slowpoke {ECO:0000313|EMBL:OMJ17103.1};
GN ORFNames=AYI70_g6192 {ECO:0000313|EMBL:OMJ17103.1}, AYI70_g7488
GN {ECO:0000313|EMBL:OMJ15088.1};
OS Smittium culicis.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133412 {ECO:0000313|EMBL:OMJ17103.1, ECO:0000313|Proteomes:UP000187283};
RN [1] {ECO:0000313|EMBL:OMJ17103.1, ECO:0000313|Proteomes:UP000187283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSMNP {ECO:0000313|EMBL:OMJ17103.1,
RC ECO:0000313|Proteomes:UP000187283};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ17103.1}.
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DR EMBL; LSSN01002779; OMJ15088.1; -; Genomic_DNA.
DR EMBL; LSSN01002144; OMJ17103.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1XR30; -.
DR STRING; 133412.A0A1R1XR30; -.
DR Proteomes; UP000187283; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:OMJ17103.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000187283};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 483..580
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 657..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1213 AA; 134984 MW; 58C83C723A38134F CRC64;
MDRILYQKYE FGGSKKGSER IAPSESEGNK FYDTFFGATA PNSSSGLLGA TGRVNQNPKN
SKNRRTRYES AIHFPGNVDE LEPTRRQIIG YYLNESYIGR KWDQLDAFFN MVLCVAYFYY
AHKLSKYNET ISLHCLVFDF ITSMILFFIF LPRYYVCPDL YDFILSPYSI ISTVSTLTPL
FILISIYFDP SILTNTVLSS GIFIYLYPLR FVRLQFSIRR VVDSTKTRAM ADPVNRHSAE
ALVIVLTTVT AITVITHVVL FKQGYAKHAE TVGFFDVFFF TAISSVTGLS SKVNPDGLFT
QLISIFIMFL GIFWLPSRMQ KVLGLIKNRS PWESSYTPEK NSRHVIVIGD LSYGSLEEFL
REFYCLDHGS KVINTFLVLM SENPPNDNVN NLINLPRYLN CVRFVLASPT SGNDLKAVCA
EKASSIFILT GKNSDSGSLK EESKKVMICL AIKKYLLSKS AEVPIFVQAS RPETSLNLSF
MSKNVLCVPE LRSGLIALGT SIPGFASMLV CLVTTISDNI LDGITKIAID EKKSAFYDEY
IDGLGQEIYT TKFSPFFRGM KFNLAAQYIY KKYSCILFAI KVNPDYVNGK SKIPITGAAD
EVFLNPSDYV LTGLETGYMI NSDKSVSEEI AQLTDYNFSI PESDYGECDS FMNGKPINMA
PSSSSRIKKG AKKPNKGTSN ISSGTGKSLR FSINSENSDS TIMDDQKNKP LSSVDSQKTP
LVPDNESKKA AIEYLETNKT SLMQASNSSN SSLKAEDNDQ FFDTSSMKQA SESVAPPEIK
STEKAGNASS TEDSSSVNSS NAADQDIKKK IEKITDNIAF ESSGSLLEVA LMKKNNKDGS
ESKPKFKNHV VVCISDSSFP GSMEYLVGSI RKCPNSSFEA SKQKNADGYT KNSSDKEAEV
QNDIFPNMVP ILFLCQSPPG DSEKKILEDF GNVYFISGSP EHKPDLVKAN IMEASKAIVL
LSSFSGNQES VSVLSEDTDI SMVTSDSSSL ISVLNIEYLT TNNKDLFVFI ELNNRENMSF
IGAKSEFELD EGYIQTFFRP CFMAGNAFAP VVIDTLIGQC FYNNDLIAIL KNLIFSCGDI
TEDVELSKMI SSGLDESHIP KILTSVPSDL DSNVYMIDVP KRFVGKPFSD LFLYLCFAYK
GLCLGLYRNS VSVARQLDPT KKYREIEITE QKIESLESSE NVSYFLANPS PDTILNSEDK
IYYLSNEDPV EIL
//
