ID   A0A1R1YH89_9FUNG        Unreviewed;      1178 AA.
AC   A0A1R1YH89;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=Recombining binding protein suppressor of hairless {ECO:0000313|EMBL:OMJ26281.1};
GN   ORFNames=AYI70_g288 {ECO:0000313|EMBL:OMJ26281.1};
OS   Smittium culicis.
OC   Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC   Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX   NCBI_TaxID=133412 {ECO:0000313|EMBL:OMJ26281.1, ECO:0000313|Proteomes:UP000187283};
RN   [1] {ECO:0000313|EMBL:OMJ26281.1, ECO:0000313|Proteomes:UP000187283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GSMNP {ECO:0000313|EMBL:OMJ26281.1,
RC   ECO:0000313|Proteomes:UP000187283};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Su(H) family.
CC       {ECO:0000256|ARBA:ARBA00009704}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMJ26281.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LSSN01000043; OMJ26281.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R1YH89; -.
DR   STRING; 133412.A0A1R1YH89; -.
DR   Proteomes; UP000187283; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR   InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR   InterPro; IPR036358; BTD_sf.
DR   InterPro; IPR040159; CLS_fam.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR   InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR   PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR   PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR   Pfam; PF09270; BTD; 1.
DR   Pfam; PF09271; LAG1-DNAbind; 1.
DR   SMART; SM01268; BTD; 1.
DR   SMART; SM01267; LAG1_DNAbind; 1.
DR   SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 2.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187283};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          313..553
FT                   /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT                   /evidence="ECO:0000259|SMART:SM01267"
FT   DOMAIN          554..742
FT                   /note="Beta-trefoil DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01268"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          136..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          429..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..710
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          763..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1094..1116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1178 AA;  130982 MW;  C84B6C4F6DB87613 CRC64;
     MNGRVDSIQN QFNLPTQPQN NIRLPSLDDS IKSKRKIDFD NFFSKKKLYD SQNLSQSTQI
     LPLSKDSYDR IITKKPRTAL DYKFKAYYSL ESHQYKNEHH RIVPINHSRP YSSPDINLDT
     NSNVTPANNY NQLSLNNSHS SPTNTTTNFE SNYTNSSNSH NNISSSSFDK IISFDSKETL
     INKKFNLSFL TNGNAKSIET PSQKHPISKY NDLQKVPTAS PELSDSSSAS ISSSSKIMSI
     KSLLETKELP SDSLITKIPS NPLKLLNTNS QPNNLNDIIT PIPKPLVTYK GHYVPLKTVW
     NDYVGDSIDN IVTVKIFYAT VAQKSYGNEK RFLCPPPAVL VWGLGESAAI LGQSLVEMHI
     VPGKSLRPRT NIRDHINSSG AFRDNSHSAN SAKNQRRLSG VSETQLMVSN SPLSMSNDDQ
     IYSRLSQLSK TSQSPYNNNN SSDSVQLIKP NSNKFSKKSE AEFVTNTRFD SDGRYISANN
     YIDSYNFALF KALYVGDLGK SKEFRLRLDF LLPPKMLKKG ETSPNKAIVE LLSGPMTIIS
     KPSKKMNSVR SKGFNIKKGT GVCLYNRINS QTYRTKFMTV DRLSCDWSVV SENWLAFRIV
     YVNNKGVEII SDNPTLDYGS LIVLESHIFG FRSPVMIVRK VDCGNLFLNS FSPVCQMQKI
     ALELYDTVEQ KGTKKFLNVP AEISNLSSKP DTDTTTNKSN KQGKKKTDST SHQPIVFDFL
     SASHSNNADL PEVISIDDSF CWTIVGVECA TYTFTYARNT GLVPNNSDQL QNRNQASSLQ
     SSTRDSNSVF KSMNLTIPGY HSNHLPNSQP QNPRYSSPNS TLMHLSPTLS NDFRKSPTMC
     PSHCGSGTSS LPRISSFPDM PLQSMGFTPR YIRKMHKLLI LVRDFDPNSM SFYLDGAPIT
     KLDYEMVPKY NTCQCQLDNG NTIFNSDSSQ ICQSQLSIKS IQSPCSLTNP LVDRRLSQGS
     ISPGSVSGGK IPNKYFIGDF KYYSNTYTNS FNHKKNDDSS YDDGYDQFMF HNNNSQPCQK
     CACGCASISP CSGCSSVPTS LACSAGKKAY LGVCISLPGI LIDNTKSLSM GGSDKKLSGP
     TGFERSQNSY NTELLGYTNP KSAESGRNSS PQSSDIQPEF ISASNLPIQH SKNSERLSST
     TAYPLFITRR DGVCHYLRWA VVLKGENDVD VVSIPDVV
//