ID A0A1R2AT74_9CILI Unreviewed; 1682 AA.
AC A0A1R2AT74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Tetratricopeptide repeat protein 29 {ECO:0000256|ARBA:ARBA00040665};
GN ORFNames=SteCoe_35043 {ECO:0000313|EMBL:OMJ67717.1};
OS Stentor coeruleus.
OC Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ67717.1, ECO:0000313|Proteomes:UP000187209};
RN [1] {ECO:0000313|EMBL:OMJ67717.1, ECO:0000313|Proteomes:UP000187209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM001 {ECO:0000313|EMBL:OMJ67717.1};
RA Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA Sood P.;
RT "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT introns.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Axonemal protein which is implicated in axonemal and/or peri-
CC axonemal structures assembly and regulates flagella assembly and
CC beating and therefore sperm motility. {ECO:0000256|ARBA:ARBA00037175}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ67717.1}.
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DR EMBL; MPUH01001447; OMJ67717.1; -; Genomic_DNA.
DR OrthoDB; 927920at2759; -.
DR Proteomes; UP000187209; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 8.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR46630; TETRATRICOPEPTIDE REPEAT PROTEIN 29; 1.
DR PANTHER; PTHR46630:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 29; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 4.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00028; TPR; 16.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 6.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
DR PROSITE; PS50005; TPR; 5.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 221..254
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 470..503
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 511..544
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 921..954
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1126..1159
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1340..1680
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1682 AA; 199886 MW; 4BC699CBC94A821A CRC64;
MSFTGNKITD EAKALELLGD NEYRVGNFQV AHSFYLKAYD INRNPGDLRL YFKITETLFS
TCIQLYQISL SDLKIPKKCS KLCLKMMQGR KYDQILLDKL NLIKLCYYIK AKKDDKAIQL
LHFFNSIESN FNSKIFFETY IGISRFLLMN NEIEEALKTL KKCSKVNKNI LKTNYQNQGF
IYYLLGGIYF DLNNNEKSSK NYIKFLNLYE RELFTDIIFV SEGYLYLALL YVKINSNEKA
IENFEKCKNI SKNMENPDLD TLKLIYHNLS ELYNKMNDKQ KSFEEIEKYV EVLQLISPDH
PELESKYIFI VESYCSLNNF QKQLEYYKKF KKLMIRKLGP KHEILTQVYF YIGVLYNLNN
MPQKVSKYYN KLLVLLENTP DGDKNKLLYA YFYFGLLSNS LGENKAWGYF KKCRKILREN
PGLINEKFTI TYIKLGKYYL IRKAEKAVKC LEEYHIFRKD LIKYKYNHLI DLYITLGLAY
KNIEEKEKAI EEFEKCRQEL NKDSLNNSLF YEKYFNLGKL FSDLKENSKA VDCYNKAIEI
YKKNNNLFTY FDTVCEAYME IIELLAKMND KEKIVFYCKD FKGKLKKIMK SDHSNLELSY
YYLGCLGEIA NKINKAQKYF KESIELARKS KNYVLLSRVY MKLGILYFNE HNKNNENIKK
TFEYFKLCLK LKIKFKLYDT KLAEVYLYIG KLYLIKNKPI KAEKMFENCR KLSEKILTPN
DYFIASVYYC IGLMHFSNAK GAIEFLEKSR SITENIYSDR HTDLLLIYKH LSIEYYHINN
YKKSIKYSEK CKNLINSFSS PDKLSLMEIN SFLFKLYIDT NDFEKLNSLN MEILQSSFFD
SLSVLFSKVF ITKFSLFKYN VRFLNSIEEI IGSNHQSLQS FYLEVGNLLI YANLYNEALV
YYEKYMNISK KFFKPNSISL ANAYFCLGNT YISLKNKPKA IKFFEKSQQL LENYYPKNYF
ALFQNYELLE RLYQEINEHT KAAENFRKRK YFEQNYKKQL DLGKNNFIQT LNIFTQILQK
LINSNQNIIQ NIISFLSNIP SINYDMISMV YDTIESVKTS YFSVKLKEDF EDNTTGFLNE
FSREKQLFNY GLIYDLSSDF KNAIKYYEKC KEEREKKMGE NHSDLASIYN LLGNVYFEVG
EKKNALVYYE KCRNIKEKLD PMNIDLVIIY NCLFYLYSDS NEPRKAKEFL NKSLEIKKKS
QIVQKNAFFM IVKFFYNIEY FISDLNFMKI IRNLYSVCKK IKENKISRDD PYLKLDLNLH
LELISDKLDM KNKFENSLVI IEFIEYCLFL PKCINNNRQA IIGLSEIFEH IDQKKNINAS
NLMTDNIKKY LLNYFNIPNE KKSSTQHEKS FSLVKHKRDK DYLYFESDKK LIVPFKNCPK
FFPNIYNKSL SYFKNIDKKK KSLKIFEKKY KGIYGDWKYI NSIYKEIKFL KMILKKNPIV
PSVYYFRLIK TDSANILLGV NDCGDNLKNY VANPNNHISE REAKILLFNI MKAYNTLYEN
KIVHSDVSPY NILVKSPEKV FLCDFSDSFI CTEVTENNPF PTIWPKKNVT VDFLSPEKKS
WSILFGSNPI SYDPFKSDVF SIGLCFLNSF GVDIKNLNDY DDSFYGYIYE ILMNGYDNFV
KDSLRRFSFK LLRNRLQKNI DEIVDEFPLE SLREILKNML EVDMAKRPSI RHVYKKAESM
GL
//
