ID A0A1R2AWZ3_9CILI Unreviewed; 622 AA.
AC A0A1R2AWZ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Shikimate dehydrogenase substrate binding N-terminal domain-containing protein {ECO:0000259|Pfam:PF08501};
GN ORFNames=SteCoe_33330 {ECO:0000313|EMBL:OMJ69049.1};
OS Stentor coeruleus.
OC Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ69049.1, ECO:0000313|Proteomes:UP000187209};
RN [1] {ECO:0000313|EMBL:OMJ69049.1, ECO:0000313|Proteomes:UP000187209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM001 {ECO:0000313|EMBL:OMJ69049.1};
RA Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA Sood P.;
RT "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT introns.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ69049.1}.
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DR EMBL; MPUH01001247; OMJ69049.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R2AWZ3; -.
DR OrthoDB; 865at2759; -.
DR Proteomes; UP000187209; Unassembled WGS sequence.
DR GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR001381; DHquinase_I.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_DH_fam.
DR InterPro; IPR023000; Shikimate_kinase_CS.
DR PANTHER; PTHR21089:SF1; BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR21089; SHIKIMATE DEHYDROGENASE; 1.
DR Pfam; PF01487; DHquinase_I; 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR Pfam; PF01202; SKI; 1.
DR PRINTS; PR01100; SHIKIMTKNASE.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS01128; SHIKIMATE_KINASE; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 373..453
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
SQ SEQUENCE 622 AA; 71506 MW; FAFB285D90B7D208 CRC64;
MRGVGKSTFG MKLAQEIGWE FVDLDFLIQE DLQIDSLGEW ITDNGIDNFR NLEYVYLQKC
LLFNKTIIST GGGIVEHLQA QTLLMAHYPV IWIRTSLENI SSNLENKTSH RVPLNIYEAY
AKRVPLFEKI YDYQFNYSTL CVETNSENFN LFCYKVLGKK CPLPNDFSNF GCVSSSEDLD
VIEKSQYLTA VEIRADFYES IENSYKDLNI VKEKLKGGLS IFTFRGNVDE KYWEILMNAG
KYLPDFIDVQ FEFGSKWLEN FESLRLAFPS IRIILSYHTE IHNQDFESIF NFMCSLSPDI
VKFISPCFAL PLTVLPHIHF SLGLENLVTR IKNTYFSPVR LGKSTGKGQL SYEELKNFQL
SLNIMPEKKC FYLAGNNISR SPAKKLYNRL FSSYGLDYTY EFLETNSLDE VIQTLKSPYC
LGMSITIPYK ESIIPYLDEI SSEAKILGAV NTIIKRNGRL IGTNTDWHGL YYPLKFRRIH
KTYNSAAVLG AGGTSKAAIY ALSKLKFKIT LWNRSKERLM LGNWPCMITQ DLDEIKNANV
IVSTIPGNAE VLLPWLSNKH IVLESAYFPD ETFIGKQANQ SGAVLITGKE MYLYMARYQF
RIFTGKDISK EIIRNRFPIF KN
//
