ID   A0A1R2B547_9CILI        Unreviewed;       517 AA.
AC   A0A1R2B547;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN   ORFNames=SteCoe_29886 {ECO:0000313|EMBL:OMJ71795.1};
OS   Stentor coeruleus.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC   Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX   NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ71795.1, ECO:0000313|Proteomes:UP000187209};
RN   [1] {ECO:0000313|EMBL:OMJ71795.1, ECO:0000313|Proteomes:UP000187209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM001 {ECO:0000313|EMBL:OMJ71795.1};
RA   Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA   Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA   Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA   Sood P.;
RT   "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT   introns.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMJ71795.1}.
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DR   EMBL; MPUH01000955; OMJ71795.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R2B547; -.
DR   OrthoDB; 50947at2759; -.
DR   Proteomes; UP000187209; Unassembled WGS sequence.
DR   Gene3D; 1.20.5.190; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45641:SF20; PUB DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR   Pfam; PF00612; IQ; 2.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00015; IQ; 3.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50096; IQ; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT   COILED          377..411
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   517 AA;  59778 MW;  A2729848F97E71D7 CRC64;
     MSESRLHIEG NILTLNKKAM ENLRKNSFAD AYECLNEAEK ILKQTSADDQ LWAITLNNYG
     CYYKKVGKHQ EALACLKLAI EKDKKSNKDQ VNLAGTHLNI SSIYSQNNSH ETALKHATKA
     LKILQKCQEK SSNVITTLII SYHNTGLEYE ALQRTLEAMQ MFKLGWELGK DKLGENHLLT
     LSLKRSLFSL GNSSQTVEAI PCIKLSKVSI RKPQTSIGLS RRKCASSSLE PKAKRENFPQ
     IQDHYFLKEN LSGTHYEKSQ KKKITLHSAD KFKSPSFIPT TKRKPVQNFS KKKYEALQSI
     VDELEGNIPK IPQIPQKDPP ISLNNSFHKY SKAKSPHEEQ RSSSIGIQVE LIKKVNDSIF
     GISNEWKRNK GITWKKKENI ITKVQKAENK VKEALKDIEI VKQEKVLLEK NEKKELIPIP
     NKTKVEFFRH RHLHTIYEAR YEDQLEAVIL IQSFFRMCLT RKHFKVLQNS VLTMQKSIRK
     YLAQEYFRNI LDSAILIQSV FRGHRVRKIY NFLLNRI
//