ID   A0A1R2B7F3_9CILI        Unreviewed;       481 AA.
AC   A0A1R2B7F3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Eukaryotic translation initiation factor 2A {ECO:0000256|ARBA:ARBA00013819};
GN   ORFNames=SteCoe_28944 {ECO:0000313|EMBL:OMJ72585.1};
OS   Stentor coeruleus.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC   Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX   NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ72585.1, ECO:0000313|Proteomes:UP000187209};
RN   [1] {ECO:0000313|EMBL:OMJ72585.1, ECO:0000313|Proteomes:UP000187209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM001 {ECO:0000313|EMBL:OMJ72585.1};
RA   Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA   Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA   Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA   Sood P.;
RT   "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT   introns.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the WD repeat EIF2A family.
CC       {ECO:0000256|ARBA:ARBA00009573}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMJ72585.1}.
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DR   EMBL; MPUH01000889; OMJ72585.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R2B7F3; -.
DR   OrthoDB; 22264at2759; -.
DR   Proteomes; UP000187209; Unassembled WGS sequence.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR011387; TIF2A.
DR   InterPro; IPR013979; TIF_beta_prop-like.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR13227; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR   PANTHER; PTHR13227:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR   Pfam; PF08662; eIF2A; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          210..397
FT                   /note="Translation initiation factor beta propellor-like"
FT                   /evidence="ECO:0000259|Pfam:PF08662"
FT   REGION          443..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  54414 MW;  552FD4DF81ABBFD8 CRC64;
     MEKTQRVHEF LCRTRDSIRV IRGLSQQENI VFASACFVCL FSKCGSKLAI VDLHGVKVLK
     SSDFTELMSV RRSNVQLLHF SECAKYLVSW EKPQEEAPNL IIWDTTTGVP IYSLVQKKFM
     KEYWPTVIFN ADSTRFYVKG GSDLCVYRIP EPQPLLIFNQ IRVTSFFTSP KTNTVIIYTG
     DSKGEGSKIS ICTETAAGLE KTTELGIIYV QEIKVLWNKD ARRALIWCQT DVDTTGRSYY
     GEHSLYIYTP EPKLKQVKTT EGPIHDVQWN PVDNEFIVIS GFMPATTNFF NLNGNKKSEV
     AKHHRNTIKW NRFGTLVLIA GFGNLHGEID IYDKETMNMI GHCRASSTVY CEWGPCGKVF
     IAATLCPRMR VDNGYCIYKY TGELLIRIME PTELWEVAWT PQIFVFEPLT PSNKEQVVVQ
     KKTYKPPGSS SGFAAHFKSV KESASGKLQV QHAPPPADFI PGMAPEPAKK KKKKKKPAAG
     K
//