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Database: UniProt
Entry: A0A1R2BKY3_9CILI
LinkDB: A0A1R2BKY3_9CILI
Original site: A0A1R2BKY3_9CILI 
ID   A0A1R2BKY3_9CILI        Unreviewed;      2594 AA.
AC   A0A1R2BKY3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-JAN-2019, entry version 9.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OMJ77245.1};
GN   ORFNames=SteCoe_23193 {ECO:0000313|EMBL:OMJ77245.1};
OS   Stentor coeruleus.
OC   Eukaryota; Alveolata; Ciliophora; Postciliodesmatophora;
OC   Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX   NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ77245.1};
RN   [1] {ECO:0000313|EMBL:OMJ77245.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM001 {ECO:0000313|EMBL:OMJ77245.1};
RA   Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S.,
RA   Prabakaran S., Witkowska E., Larue G.E., Fisher S., Freeman R.M.,
RA   Gunawardena J., Chu W., Stover N.A., Gregory B.D., Nowacki M.,
RA   Derisi J., Roy S.W., Marshall W.F., Sood P.;
RT   "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT   introns.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OMJ77245.1}.
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DR   EMBL; MPUH01000585; OMJ77245.1; -; Genomic_DNA.
DR   EnsemblProtists; OMJ77245; OMJ77245; SteCoe_23193.
DR   OrthoDB; 94996at2759; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 2.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2262   2284       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2304   2323       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2329   2355       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2376   2399       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2450   2472       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      105    158       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      300    402       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED      924    944       {ECO:0000256|SAM:Coils}.
FT   COILED     2567   2594       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2594 AA;  305104 MW;  BACCE4FAAF22B803 CRC64;
     MDSKYLKYGS LITLSTCEGY FLYSQGFIDS SPYLREQTRD FSEFTGAVFR IVPQSLYNVQ
     SSIIQFIKET REGDFYSKLN ELNKMEENLE GEIKTNIHLY NSYKGQIVTY NSLVQLEHFT
     SHKFLTLHSK SAEAEKDNFK VSFKNFPSEN SHFRIVPSYK FQEYGSGKIK IFDKIYLEIM
     IPNLRKIAWM HSSKGHFIEV VSSNINAFGS VADEQYKAIE VNVSLDQRTR WSIGIYGDLP
     KDLKFLSCGD CIWLNMPEEN VSLSVYKKRW EVEKYKLMYT NALNDTNGLW KIEFEDPFKG
     GPVIEGKKYR LKHIVTGKYL AIGVNPILKS TPGSSTLWRF MPFKNEEFIK SDELTYIIND
     KTGYAIKLLG KDEMELSGYL DENCIYKPCK ANNEVIWELL FLLHCYPILI NFPKKLIQHS
     HLSLSENIRK FPEFRKHCDI LLICLKQLKL FVGNRLKSMI GIDNHFGEVT STRQLMLKQQ
     HFFEAFASIL EHSVPDDQYE TFKRISTKQV KERKLNKTYG DIESARIRTI SMIISQIYSL
     LIKICERNSD AQRHAYKFID IYIKHIGLDL GATDLLLAII RNNEEIMLEV HQNIRIDIIN
     FYSSMLLKFI LEKKTEFIGF LNNICVYKGE PVSANQEKVF ASIFKNDEIV KNVLINTETD
     GNELFIFVKG IRISLLSCFE DGRINGYDIE MQYLTGLLEL YSNLCSGRNF ESSALFIEKY
     PFEVLNLMIW NSHLTIDIRA SFCKLMLAMY IDCFMREEVA KPELIKIINT GDYLKGPRND
     FVDVLVHKNN SRPMIDRFSN LRAFELSEAS LPDLIEKIFD YFETSYFHSD FSTERQFEDF
     IYEFSEQETN KPYLKKFYNV FTFEILQVTF KLIKFQKFSL TTGVNESGPF NNSISTNSDM
     VRLMRAILPL LLDVRVNDIY TKTASSYKKR NKKANAKLQK EKKISYIHYL SSIFKDSNSL
     NDPVIRSAAN LKNFLSSYKQ NPFNGLEKKM IEHRIKLKIC KIIEYFLDMR QDYLINNVIQ
     WYNGLEDYRT WEIKDLEHLL PNILVNSECK EIFSKVTQNI FKSYYIPQVP DINSISQNSY
     IIPSLFNSFI YCDNYKLQTQ ILSIIFRAFT QRKEFLKNIK KLHVIFKPQD ISLLNWIKSS
     LLTFKHHSEQ SELWLNYWNS DSQYNKHKEV FDKMKKILRD IECFLYDDVT MTEDGPSNPT
     SKTLSKSRQE MLFYLNAHKF IITLLKDGVH KLASIYNEKK QDELKEACGL LSDLFTSCHI
     VLKRFVYNNT RNQKKLHKYM NVLLQYLYLN LGQVSLICEI YRDNIVLVNS ITEDQIIFFE
     ELIKKYGRQA HFLKILEVVQ VVKQKPIAFN QRMVMSLFIK EKLNTYMLYM NEDEYPSFVF
     NIGEKINLLY KDEPFEYHAM LLKVLSNCGF GASGILFNEI KCQNIVSLKN IFRILYKCEE
     DPISSFQILK MPMLNFFFNV YLDCEITNLQ LKSYKLFFKY IGMQCQVLDS LDETTDTYIE
     FLAIWVKILN KYRSNYIKKI NRSYYEQDDV KAIRYFIECL IRNCTKLTKK LTNQLVTEIY
     ELSKFFGEEF NNVEKIEFSN NTNEEDDPEI ILHRVITNVD HTSMKSVQIE LWNQVRNAFN
     TNKIFKTRIE DEEYALLLYI HNSNILFPEI DFEKIIRSLI SFTRLSRSQK PPISVQIMSI
     QLLEKIISRP ICNKYDIEKK LKIDMQYHLS FLGLTNVILN LMVDSQLEYS VFKSLISLSV
     QLLDGGNPQI QQEFYQYFLT TSNSEYFFQR ISQILKKKIE KIAENSSNEN RKNLVYKSKN
     FPLKKLLRFL QLLCEHHNHS LQVYIRYQEK SHTSYNLVLA TIDLLEILMK KKKHMLFHVL
     SQCFETINEF MQGPCLENQD EVVNSKFLEI TNELLSLDET SSTIQYYRGL HITSCNNETS
     MSGNIEQEEI QISELSGWMI AHLKYKCLIT ILSIFEGRKD TYAATRVIRV INIEVLEENI
     KNLYMNYQEY YKWEDYYDFD LFKHIKTNEN YDFSISNNPQ DENPNYYSLV IENGFLVLNL
     LKTLLDSNDP DCQEILSCEL PGFLGIEEEN FTAVVHKKKI KKTFTMRAKE IKESVQQYKF
     EGKEIEKNNE NITKAAYEFF EKHTGNVEVV FNREIFRVYF YYPPEYKGLT KEIKEHFHRN
     AIRDSDQSKL KYMLDSTDEL IKKINHEYFI KNIMKKSKTI HIIATNVDNF RKIAFFLTII
     LNLIILTSYS HERDYESVLT FTPDDEGLGN NLTVALLRSF GIIQLACCAF IVAFFLLKVG
     PLLAKQGWEL KGSRLYFLRS GKGILILSVL KIVQIISTTF YILSNVDVVY YILYAVFSIL
     GIIVHPFYFS LLLLDVIYRY PALHNVVNSI YLPRKALVLT FLLLLVIIYI FSIIGYWLFF
     DYLSPDCKTL LQCLLTIWDR SFKNDGGIGG YLGYPITPSY DAGRFFYDNI YNIIVVIVLM
     GVVQGIIIDT FARLREGQEF STKDRESKCF ICGLQRDFIE KKTSSGFEHH ILNDHNEWNY
     ILFIAYLKRK NESEYSGLES YIKEQYEKNE LGWIPNQICL SFKNEHKQDM VERIENINEQ
     LDSIEEQINN FTNP
//
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