ID A0A1R2C216_9CILI Unreviewed; 910 AA.
AC A0A1R2C216;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=VASt domain-containing protein {ECO:0000259|PROSITE:PS51778};
GN ORFNames=SteCoe_16119 {ECO:0000313|EMBL:OMJ83027.1};
OS Stentor coeruleus.
OC Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ83027.1, ECO:0000313|Proteomes:UP000187209};
RN [1] {ECO:0000313|EMBL:OMJ83027.1, ECO:0000313|Proteomes:UP000187209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM001 {ECO:0000313|EMBL:OMJ83027.1};
RA Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA Sood P.;
RT "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT introns.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ83027.1}.
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DR EMBL; MPUH01000318; OMJ83027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R2C216; -.
DR OrthoDB; 247456at2759; -.
DR Proteomes; UP000187209; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 879..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 672..854
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT COILED 132..169
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 910 AA; 105685 MW; 23D20F412A238D8A CRC64;
MSTLGQKISN ACKILDSEKQ GIKSYKEKAL MIESLWKDFN VLLKTLIMSY VNFGRKHTDE
SETLLSYRNS FAKSISLSKI LFIIGSYSSH IGNFYSTQSH DLSHSLKSKS SAFSLEIKFF
LENIKEKSFK TLENLSKILS ELKSEHIKLE KSRREHDEVK ILLLNLESNT VCNDKKLEIG
LKNSQFKLSS QVLAFEESIL ALIELFYRNI RDLKDQSKHL HESLIVLENK CLENIQNIVD
DIKRLAFTLS EYRKNTSENM KSALLIVPID ESVDTSFCRD QIIEISDKKL EVLKYLKDYM
TIIADVEDFI SFSYTKAKKA SFLNQNATDL VSNTSAILEE LEDIFTMHNL YAEKCRENVL
KPLESVFRMH SSLNSSIKIS IKKILISYKK AEEFLMRSPT KESSKSSGFK TSEICEINEV
LNDYILREKK LLSSTRAIFL TLHDQSLEFY NTLQDLQTKI VNSSKTIRHT YTLRSLSIDF
SNDNYYYDET ISILKDKSRN NFIINSDESF SSDDEEFNRR FSIEIKEPVI STYICAFSDG
ILLHGKMYIT ANYLCFYSHF NSSTILGGVT SLTIDLSHIV LLEKKYNAFI FDNSIEITTK
ERKYFFTSFV SRDEAYTILA KLLMLKERKS FLIKHHVDFI IEERKGRLCL GRMIKDKKDI
QSRMFPDNYF FEEVFVPELH TEIPIYKIYQ LFFSDNSYDF HYNYLTEAGD IDIDIGKWSV
PPPDFYIEKS SGDVWNNIAT RTVVSNHKLK ERLPLMSTHA LLKENQTIYF VSEEKFVIEG
EFEVHAPFGD CFKSYMRWVI SGRDNAIIQA RYGCVFSKNT IFKGKIIKEG AKETVSTLNG
IWWRLAEREI KKDQGIFKEE EETQPQVIEK PKAKLEITVG LYGIIALLVL IIAKLWQKVS
LLEQELARFQ
//
