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Database: UniProt
Entry: A0A1R2C5P1_9CILI
LinkDB: A0A1R2C5P1_9CILI
Original site: A0A1R2C5P1_9CILI 
ID   A0A1R2C5P1_9CILI        Unreviewed;      2589 AA.
AC   A0A1R2C5P1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-JAN-2019, entry version 8.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OMJ84307.1};
GN   ORFNames=SteCoe_14590 {ECO:0000313|EMBL:OMJ84307.1};
OS   Stentor coeruleus.
OC   Eukaryota; Alveolata; Ciliophora; Postciliodesmatophora;
OC   Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX   NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ84307.1};
RN   [1] {ECO:0000313|EMBL:OMJ84307.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM001 {ECO:0000313|EMBL:OMJ84307.1};
RA   Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S.,
RA   Prabakaran S., Witkowska E., Larue G.E., Fisher S., Freeman R.M.,
RA   Gunawardena J., Chu W., Stover N.A., Gregory B.D., Nowacki M.,
RA   Derisi J., Roy S.W., Marshall W.F., Sood P.;
RT   "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT   introns.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OMJ84307.1}.
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DR   EMBL; MPUH01000273; OMJ84307.1; -; Genomic_DNA.
DR   EnsemblProtists; OMJ84307; OMJ84307; SteCoe_14590.
DR   OrthoDB; 94996at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13833; EF-hand_8; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 2.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2194   2214       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2235   2259       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2321   2345       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2365   2387       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2447   2470       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      113    166       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      235    286       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN     1494   1529       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     1530   1565       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    1507   1518       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   2589 AA;  298062 MW;  E9235F171A67DC84 CRC64;
     MDKIDKIDEH PDPPKKVGKV AGSLTKEELA TDKSGCVKIG DIILITIKID SFNGMISADG
     VISQSVTAIP KACEGETGAN VLTRSCLFRI EKAMKIVKNT GNKWKSELKL SIGKTVTYGE
     RVQLRHMHSM SFISMNSSVM AAEAGCLQIE MNEESNEISW FEIVATSKLR KEGEFIHYAD
     SMYFTMTSKK SLYYLHADVS SQITSGSRLR INASGTPNAW KLRRYASFTL MKNVLGFVQT
     GDSFRILHKL SAGYLATNEK TQGNMPEVFI EKGNLTSNSL WEIQKTATFS GGIAFWQASY
     RIKHVATGYL LQEIGSSIVL TTKASEEGTL FSFVPDQQLE EPHMKFGIAI CIQTHKKRYL
     NLELPDIDEN DKAKEEIRFK IEVISSTRNF TGVAFVFEDV AEEKTAHVYR LSLVNPYLAD
     LYGFLGEIVF DDGYFRENPE RIKKLKDRCE GFAGMIENIS KHIIFKADAE ASMKERQDAI
     RELGILQLLL DISALLHDKV KESKKSSKVI LLSLEKVYKL IYHSIKGNQQ SSQQLVLKEK
     VLIGQLAHGL SRGVGHILKE IFKYATEISQ ITDESFTKWY VLLKTITDEN VKEQALYLSI
     LRFLCQYRNT GVQKYQSLAL KALANPHNDF TILKFHILNK RAVIELDYPT KSCNLKKFLN
     DNPLLHKDKL VVDEQNLLVE QDPINALFYI EDLSKIPKYA GYVACAVEFL ANVCLGRYSK
     ALHQLPIITG ISLPHIAMVL KNPEVSEKIR SAYANLCRTL IIDIDPFVPC SQHTDRCYQW
     DSLKGFRDQT IAQRMEVLSP IREILKNFWD KDGITIDHEN PGKSISLVVS MLKMTRYLID
     LGMENDEFIE FFMQPLCFFM MKEAGDDDHW STGFMVSIKL SIESGMSPSL ENQLAVLHEE
     IMQTLKVITV RRQNVHVQEM LELFKEDLVN KYDIEFLENK YKSIVQKLDW NISVKYFDNV
     TDAIGNVTTV ENEKTYHLGL YLLELLFDVS DGKNKQIHDK ALSILLKDLN FTQILADDLI
     QCEFLYDAES SEIYNNMLLL TKRLESTVAL LVQEQNENSD SIQVHDAIKD STIIIQDTIN
     IYKNLDEKSL FQNLMFHSGA YRLLMKILNL NYSKIMTTLF TKTIKTLFYF CKNNRRNQRI
     VHKLVKRIIE LIPHLSVTRL LCEAVADLRE ESIGEKALSI VLKRIESEGC TIEYLRFLRG
     FLLDFDKKRI KTIQVRVLKA IFNSPAIKNI VEDPLLDVFH PNSFFEPNQM NPEAFLMHLE
     LMKTVIACTI ENNFGIVQCR RLISPLTLRH YMTKPELSYE AREIYLKYLQ LVFFSGIDGE
     VEPECNINIL DTILDEVFIP DVKKFKPLLQ PLMEIGKKGG FNDIMRKKPH KIFTPNNNEQ
     EIIDYWNYLC HKSTWCDYEG GILNTFGDIF IENGMSLDEK MEEIIRQFKV CLYELSDTLQ
     SIETTHKEFK FSRLISSVNI LREALPRAPL VSDEAAKAPK MNPVLEALQK YIVEHKLTLE
     DAFSHFDVDE SGNIDFEEFR TSIRRLLGNL SSSEIEMAFN DMDDDHSGTL KFSEFANKIR
     KYFSKNPRVI STRKQINEQN FTLDDSNTVV DIHNKTGKKE ALEEFIKKFV NSCQARDLIA
     LVEKIKEKYI TPAIETGDKS IAEPLCKLYQ VFTRPKEKIY LIRIFKSLMP SFEPKVVIFD
     EPDAEEARLK SIFIVHQELL AEVGVLKIAF SLIDQDNSID LVKESVELIL LLLKYGNSKI
     QMIFLELLQS INTSKFFSYI RTQLRFTRDS IVKRAHEDFL EDPDLTIDKT LVNPETDYSR
     INAPQGVKKP TFYLAKHLLE LLQLCCENCF LPFQHYLRCQ NPQNPQNKGV NINMVEEIAL
     FLLDIRQLGG NIFSDPEAAN MVIQCFETLI DCCKGPCVEN QILLGTKMKL HKFINSTIHI
     YNCNRDFGAI FKSAVRLLSA LLEGSFPLEI AKAMIDHLDF ELLANIALEI YREYVVVKKS
     ALLQELIVGT GVSSKLMQII RRSYAYFKRN LVELELEEWI MISIGFEITI ITVKLREKFR
     DVEELRWLCF FDEQPGNESS ESSLPYILNS ISDLGGYSES ITSDLKKTLR FILKLNNSEY
     DMNEAYEFYA SLTSSVEIYK DGQIEKCYFQ MPTCIVYLNE HMRKKIIYGM NRNSNEEKIK
     SFVFLCNKIL LELNHLQTIS RVGILGWMTS KYRFFATTLF VSIICANIIV VLTVTNAYDR
     DYSSKNFSGD KLMNFLGFII VFTSIIMYLL SILFTYPVII FEKVHQEMQS QNTYQAIEGG
     LIGTVKLQQR SEGLTEKLIE VVDYTKYVFI VLMNSHNLVD FALLILSMLG WYNPFIYGFM
     MLDILRRSTT LKNILQVITK NKRSLLLSLL LLVIIIYIYG VLAFAIFSEY YQEKIGNYSF
     NTYCQTLWLC FTNTFNLGLR STGGIGDVLY PAFRGDKDYT SRLFFDLSFF IVVIIILLSI
     IFGIIVDTFA ELRDARRETE HDIDNCCFVC GRMKHEFELR GSGWSQHIQV EHNIWSYLAY
     VIYITKKPMN ECDGIEKYVK GKIIQNDVTF FPPTAICLEE KKEKKENKKE GVLKGLEEIE
     EFIKSNWKK
//
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