ID   A0A1R2CM20_9CILI        Unreviewed;      2256 AA.
AC   A0A1R2CM20;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=TOG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SteCoe_7641 {ECO:0000313|EMBL:OMJ90062.1};
OS   Stentor coeruleus.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC   Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX   NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ90062.1, ECO:0000313|Proteomes:UP000187209};
RN   [1] {ECO:0000313|EMBL:OMJ90062.1, ECO:0000313|Proteomes:UP000187209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM001 {ECO:0000313|EMBL:OMJ90062.1};
RA   Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA   Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA   Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA   Sood P.;
RT   "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT   introns.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GCN1 family.
CC       {ECO:0000256|ARBA:ARBA00007366}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMJ90062.1}.
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DR   EMBL; MPUH01000111; OMJ90062.1; -; Genomic_DNA.
DR   OrthoDB; 6844at2759; -.
DR   Proteomes; UP000187209; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR   PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   SUPFAM; SSF48371; ARM repeat; 3.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000187209};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          1465..1501
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   2256 AA;  255781 MW;  36D00CC9F0AA565B CRC64;
     MESLESIETA LSLEWSPNSL YHLTETLIIV LSTPGIPKRH LSAIWRISRI LKNKISPETK
     SNIFEAFQKA TNNFKLQLKF YIRLGLSNDL KTLSKLVYLA HKNTENLSKL PKFKAELDLS
     LKSQEFFPGS IYLTRPIPTN ELLEYFNNKY LIDKVSKDDL NLLKLFRPLI NQISSEQYLE
     IFHNSLKRFC IRSSSSLSLI TEILDLFQCD FSNFISDYTF PTLLEYLNKT EDSVNASKLI
     KTLLSKCKDY KKFVEQLCGI RNANEAQTIN LMHIVSIIPK GQHSSLLVDY VTSMSQRVKT
     ESSRGLVALA LSKHVDINNA PGELLKANLT NPYFANLVYL LGLELPLNYN QNSPMMLISV
     LSLKIPDQLP QKIVNFLNEP ISALFSLQNL TEDESFALTR CVRLGLKVYP NNPHLLKRFA
     KGVVSKYKKI QDYCLKNWPD VQLAALIPFI LEHLNDEVHL TSFIRVFYNL CRLICGKLKN
     SDDVDSFLQL LTTESLINSK RTKFLLKKCS KFLENYSEKV FKTSTRCVGL ALSLPNYEQK
     LDKLLEELNY DKVTESQQIL SYVISVFEDP NFDEIGKFNN QCREILKSAN LPLEPLDQNS
     VTRALNILWQ RSLNRSAFIL HSFINALHYQ SYVKTNSSFF NTMCFKVLPI VFKLTPIVND
     FSSNSSYQGF QNLSLSGACW DFLYALTSSS PNFGQISWYF TAALFKSARN QWSDKALSKL
     FKFVEEKISI SQIENSEGFM MERVFLWVLR QSGTSLRATA LTVMVDFLHA GKISNMDETI
     QEICVLIESY SSPLLNSLFQ PLLDRIEPKE WKAFFDILLK LQPNTKQIVL DNLLQYSKVI
     PNEYWIVTPV YLCLFDETDL VSSSAADVWE KNKLQLSLEI VENHVQEYLY DENLELSLMT
     ALALKDAISK NPDWTGSILD KAKIQFMAHK SRIGFAKLLQ IICPGMTNKN LVLSTEEFIL
     EIGMTCTDIS KELLDVAILY LNTHGESLVN EFFTMIQQRT THQNEKIRNS AVVLAGYLAK
     FFNSEDFRIE STIDLLLKAL DMPSELLFST VSKCLPRLVA LRPQLVEALL QQEFKKLLEN
     KPKVDKRGIG YGIACLVKGG GLKCLVSYHV LDRLESIINN KKSPDNEKAG VLIAIEGLGA
     VLGRSFEPYL GEVLPFIIDC FANKDLQEQA AISTKVMISR LSAHGMKRIL PQLTHGLEET
     KWRSKVGAIE ALGKMAFCAP KQLSAALPSI VPQVIKAFSD TNPKVLEAAN MAISDIGSVI
     TNPEIFQLVP VLSKALGDIS HLSEAFKILI ETTFHHYLDT ASLSLIVPLI ETGLKSRNSE
     YKKQACQIVG GISSLIRTPS EFAPYIERVT TAMKFSLFDS LPEVRNIAAQ NLASFCEGIG
     SEFNETIISW LIESMEKSNL NFERSGAVHA YSEYLLYQDR WQEHLDHLLQ MCKEASPIVK
     ESYLGIFIFI PLNTQGKFEK FLSRVMPAFL ERLSDDNEDV RKMVIRVVQL IIQTYCKSSL
     QIILPHLEQG LFDRNWRKRS SCVTLIGEMI EKIESLSRKE NQQLISVEHK NRILASIYIL
     RADHTSNINT QAAQIWKTHV DNTPKFLVSL TPELVLRLIE ISDNNDAEPR EIASYAIQNL
     IQKYQNKVFS SYINHFLTHF SAYPKGVAFV LRTVCETASR NLLITYSEKI IQILEVLLKS
     DDIDYLHNAG GIFHDMYQKT TIEKPDPAVM ALLGKMVSYP KACKELLAFK NVGITKALLP
     KIMSAPERTI TLELVGKIIA DDLFSVKGLE NVFPGMLKEC NESDNMVLPV QIVVANIADS
     SALIQALSNM QEMISPQRQL QVINYVCKNS SMVYTSFIDK LLEMTLSNLE STENEVLAMI
     PETVKLILAP IDKEQYPDYF LVFKERLNSI EKIPLFNVPK GLEPFLPLIQ NSLMYGNIEI
     KELAARSYCE VIELTETDIL TSYAVMIVGP LIRVLSEKVP GDVKVSILDA LFLLLQKTPL
     KLKPFVSQLQ STFTKALVHN EANVREAGSR NIIELLKLKP RLDLLFGDLG TLNNTADIVT
     KSLETLQKIT KATEVPSQLL SSLCNRIINE LNYKTSNDVA IEAGKLLFMI NMDLSTILQC
     LQPNMPSIIM LSEILNKSNT DALNVATPFI DNAVRNNFDE AVQIFRLIAE AHPKESYDMA
     KKHFNDMAQN IGICIDVLCS FPEGMLCKDI DSFSGIFPAL ARECIFDDTN EEMLKNAVIK
     IFNVKKGDIK NVLKVLHLLD EDMQKQFRNW VQKFLG
//