ID A0A1R2CN35_9CILI Unreviewed; 736 AA.
AC A0A1R2CN35;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=SteCoe_7291 {ECO:0000313|EMBL:OMJ90375.1};
OS Stentor coeruleus.
OC Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ90375.1, ECO:0000313|Proteomes:UP000187209};
RN [1] {ECO:0000313|EMBL:OMJ90375.1, ECO:0000313|Proteomes:UP000187209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM001 {ECO:0000313|EMBL:OMJ90375.1};
RA Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA Sood P.;
RT "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT introns.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ90375.1}.
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DR EMBL; MPUH01000104; OMJ90375.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R2CN35; -.
DR OrthoDB; 179989at2759; -.
DR Proteomes; UP000187209; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF73; KINESIN HEAVY CHAIN ISOFORM X1; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394}; Coiled coil {ECO:0000256|SAM:Coils};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000187209}.
FT DOMAIN 9..335
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT COILED 340..374
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 481..508
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 533..685
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 93..100
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 736 AA; 84021 MW; D6E9DD0C56A6327B CRC64;
MSKSSQSGNI KVFCRFRPLN PHEKLTSDLI KLEHDSNISV TVFPQTEHSI PLTFTYDYIF
TSESTQEDVF TIAAKPIIED VIQGFNGTIF AYGQTASGKT HTMTGHDIFD PYTMGIVPRM
ISKVFDSIES ADENVEFAVK VSYCELYLEK INDLVEVDKK ALKIRQDRSK GVYIANLSEH
YVASDFDVFE LLRVGTENRQ VSCNKMNTKS SRSHTLFSLT ITQNNALDLS ARVGRLYLVD
LAGSERVSKT NAEGQRLKEL KTINKSLNTL GQVINQLTDG KASHVPYRDS KLTRILQDSL
GGNSKTAIII TCSPALSNES ETISTLRFGF RAKSIKNKPK VNRELTMAEL KLKLAKIEEE
LRKKAIKIST LEQALSQNEV TLPIDTTILT EHTDESDDLK NTDTDDFFAE LEDARNKLTT
LVDENFKYKT SSIELKSNLD QMNDNNINQT ALISVLEMKI VNMETAIYNK VELTSKLSIE
KDVLTTKLEE VQNKKLELER IYNEKLVESN DLKFQVKMHV GDDEISSEPV DLIEQLKNKL
MSEQQKYKKN QTEMQGLQIR LNQALQELTR DKRNEEKELL NREIQARNEK IKFLEDELET
ITENHRSVKK ILSEDEETLK QRTDELERTL DELTNMYKQL LAKQSSVNIE KQLNIRKITR
LNEKIKLLED ELKTKREQLM TAEVEANRFL DDMASQSIFN RIKVPIKGGG GKGVRASMAN
RLSIRPNRAY ASMVSH
//
