ID A0A1R2CT42_9CILI Unreviewed; 852 AA.
AC A0A1R2CT42;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=SteCoe_5137 {ECO:0000313|EMBL:OMJ92148.1};
OS Stentor coeruleus.
OC Eukaryota; Sar; Alveolata; Ciliophora; Postciliodesmatophora;
OC Heterotrichea; Heterotrichida; Stentoridae; Stentor.
OX NCBI_TaxID=5963 {ECO:0000313|EMBL:OMJ92148.1, ECO:0000313|Proteomes:UP000187209};
RN [1] {ECO:0000313|EMBL:OMJ92148.1, ECO:0000313|Proteomes:UP000187209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM001 {ECO:0000313|EMBL:OMJ92148.1};
RA Slabodnick M., Ruby J.G., Reiff S.B., Swart E.C., Gosai S., Prabakaran S.,
RA Witkowska E., Larue G.E., Fisher S., Freeman R.M., Gunawardena J., Chu W.,
RA Stover N.A., Gregory B.D., Nowacki M., Derisi J., Roy S.W., Marshall W.F.,
RA Sood P.;
RT "The macronuclear genome of Stentor coeruleus: a giant cell with tiny
RT introns.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMJ92148.1}.
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DR EMBL; MPUH01000067; OMJ92148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R2CT42; -.
DR OrthoDB; 179989at2759; -.
DR Proteomes; UP000187209; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01369; KISc_KHC_KIF5; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF17; KINESIN-LIKE PROTEIN; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394}; Coiled coil {ECO:0000256|SAM:Coils};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000187209}.
FT DOMAIN 6..331
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT COILED 401..484
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 527..641
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 709..810
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 89..96
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 852 AA; 97591 MW; FD13C19818FF4A5F CRC64;
MEDQNNVRVV CRFRPLNDLE CQRAQGLCVS FSDQTVCVNS QSDSAENLKF TFDKVFTPES
SQEAVYNFAA KPIVEGVMQG FNGTVFAYGQ TSSGKTFTMS GPDLEDPITM GIIPRMVNTV
FDFISDTDNN TEFTVKISFC EIYMEKIKDL LNPTEGNLKI HEDKIKGVFI EGLTEMYVSN
DIEVHEIMKE GNENREVAST YMNAVSSRSH SLFIITVNQT NSKDFSGKVG KLFLVDLAGS
EKVAKTGAAG LRLEEAKHIN KSLTALGQVI NSLTDGKSTH IPYRDSKLTR VLQDSLGGNS
KTSLIVTCSP SPYNEAETIS SLRFGIRAKA IKNKPKVNRE HTVAELKLLL AKCQEEVEKR
DRIIAKLENK LKSQGDSLLD ISTCSRQSQE KIDADDIMAE IDELKYRLEE QIDISKKLKD
NNDKLLRELA EIKSERSMMI QQLEETQQRT SYAEKSVKEQ EVVIEKLVLT KDSLEKSIEI
AMKNKISSDK IITEKDSEIF QLKQDLLMNS PQKQRKSITF AVSPAELQKV KSQNSELKKE
LELTKDQLKA TVKEYNKVID ENEILRDKQS SSYRKTETFK TVSPEVVSLK EEIEDFKMML
NQLQSESEVQ KLQINEKDIE MLKIKEENEN LKKKISDIQG TIDEILTTKP PEPQIPETKI
KSPELHKHEE NFAEMLLAKE KSQYEEQRKR WDSERKDIMH DLENRINRVI ELEITLDLAK
EAHRNLEKNI GKNEKELIAK NQYMEKYISK LGSELQKEQL LKEKIKTECE YNEKKLKEQL
DRVRVLEAEC EEFKKKQLRL ESRLKFAEEE AYNANNMRNR PSINHGNVRK PIKGGFNAER
LTIMSPIAEV GN
//
