ID A0A1R3GYW1_9ROSI Unreviewed; 1072 AA.
AC A0A1R3GYW1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399, ECO:0000256|PIRNR:PIRNR036573};
DE EC=2.7.7.- {ECO:0000256|PIRNR:PIRNR036573};
GN ORFNames=COLO4_32578 {ECO:0000313|EMBL:OMO63318.1};
OS Corchorus olitorius.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Grewioideae; Apeibeae; Corchorus.
OX NCBI_TaxID=93759 {ECO:0000313|EMBL:OMO63318.1, ECO:0000313|Proteomes:UP000187203};
RN [1] {ECO:0000313|Proteomes:UP000187203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. O-4 {ECO:0000313|Proteomes:UP000187203};
RA Alam M., Haque M.S., Islam M.S., Emdad E.M., Islam M.M., Ahmed B.,
RA Halim A., Hossen Q.M.M., Hossain M.Z., Ahmed R., Khan M.M., Islam R.,
RA Rashid M.M., Khan S.A., Rahman M.S., Alam M., Yahiya A.S., Khan M.S.,
RA Azam M.S., Haque T., Lashkar M.Z.H., Akhand A.I., Morshed G., Roy S.,
RA Uddin K.S., Rabeya T., Hossain A.S., Chowdhury A., Snigdha A.R.,
RA Mortoza M.S., Matin S.A., Hoque S.M.E., Islam M.K., Roy D.K., Haider R.,
RA Moosa M.M., Elias S.M., Hasan A.M., Jahan S., Shafiuddin M., Mahmood N.,
RA Shommy N.S.;
RT "Corchorus olitorius genome sequencing.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a
CC dCMP residue from dCTP to the 3'-end of a DNA primer in a template-
CC dependent reaction. May assist in the first step in the bypass of
CC abasic lesions by the insertion of a nucleotide opposite the lesion.
CC Required for normal induction of mutations by physical and chemical
CC agents. {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945, ECO:0000256|PIRNR:PIRNR036573}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMO63318.1}.
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DR EMBL; AWUE01021134; OMO63318.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R3GYW1; -.
DR STRING; 93759.A0A1R3GYW1; -.
DR OrthoDB; 169741at2759; -.
DR Proteomes; UP000187203; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR PIRSF; PIRSF036573; REV1; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR036573};
KW DNA repair {ECO:0000256|PIRNR:PIRNR036573};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634,
KW ECO:0000256|PIRNR:PIRNR036573};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036573};
KW Reference proteome {ECO:0000313|Proteomes:UP000187203};
KW Transferase {ECO:0000256|PIRNR:PIRNR036573}.
FT DOMAIN 91..182
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 389..570
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1072 AA; 118847 MW; 74BF5B4B739413F2 CRC64;
MSLDSSRSAN SAPQNSKRSF NSNSSNNNSK KRKSNQKTLG MAWGANSLSS SRSSFRSSPF
SDFGSYMVEK NRKLQHQFDS EASNSSHSDS STKPIFHSVS IFVDGFTVPS SQELRRYMLN
HGGRFENYFS RHRVTHIICS NLPDSKIKNL RSFSGGLPVV KPAWILDSIA ANRLLSWVPY
QLDQLASNQP TLSAFFTPKI SPASEGAFTN AICEVKYETD DLCLKDALKD VKSFEAGESS
ELRNKITEEH DSLMHENSNA QVIEEPSSSY SEESGEVKVV EPSNLQEDDE RMENNGLQSS
PEQPSASVSS HCFDNDSIKG SSRSTTSEPL KQRHSTLGDP NFVENYFKNS RLHFIGTWRN
RYRRRFPSLS NGCKKPRSEV SVDTQKTPVI HIDMDCFFVS VVIRSRPELH DQPVAVCHSD
NPKGTAEISS ANYPARDYGI KAGMFVRDAK ALCPQLVIVP YNFEAYEEVA DQFYNILHNH
CNKIQAVSCD EAFLDVTDSE GKDPQVLASE IRKEIFEATG CTASAGIAGN MLMARLATRT
AKPNGQCYIH PERVDEYLDQ LPIKALPGIG HVLEEKIKTK NIRTCGQLRM ISKDSLQKDF
GIKTGEMLWN YSRGVDNRLV GMIQESKSVG AEVNWGVRFR DLQHAQHFLF DLCKEVSLRL
QGCGVQGRTF TLKIKKRRKD AGEPAKYMGC GVCENLSHST TVPLATDDVE VLQRITKQLF
GFFHIDVKDI RGVGLQVSRL ESADTSKQGK NVGGSSDVLD TDQVGDSVHR TNSTSIGEGC
SNQISTVPPL CHLDMGVVES LPSDLLSELN EIYGGKLVDL IAKSKGQGED SYSSLCILPP
ELARDQAESS HNSGPDSLIR TAVQMKDKQH ISEELQTVPE SGAGSNSVAI SVPGDLMPSS
LSQVDTSVLQ QLPEELRADI FELLPAHRRP EISTMGPNAD DLHHPLGNNS TDNQPGSSGS
RLSTDLWIGN PPLWVDNFKI SNSLTLKFFA DMYYKAKSAD NLSSILQCTI SQSLHALDAR
CDAWSEAVHS FSELLMGYIK LKIEVDIEEI YVCFRLLKRY EVSIVEEDKI SS
//
