ID A0A1R3J4T0_COCAP Unreviewed; 454 AA.
AC A0A1R3J4T0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE RecName: Full=3-ketoacyl-CoA synthase {ECO:0000256|PIRNR:PIRNR036417};
DE EC=2.3.1.- {ECO:0000256|PIRNR:PIRNR036417};
GN ORFNames=CCACVL1_07594 {ECO:0000313|EMBL:OMO89837.1};
OS Corchorus capsularis (Jute).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Grewioideae; Apeibeae; Corchorus.
OX NCBI_TaxID=210143 {ECO:0000313|EMBL:OMO89837.1, ECO:0000313|Proteomes:UP000188268};
RN [1] {ECO:0000313|EMBL:OMO89837.1, ECO:0000313|Proteomes:UP000188268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CVL-1 {ECO:0000313|Proteomes:UP000188268};
RC TISSUE=Whole seedling {ECO:0000313|EMBL:OMO89837.1};
RA Alam M., Haque M.S., Islam M.S., Emdad E.M., Islam M.M., Ahmed B.,
RA Halim A., Hossen Q.M.M., Hossain M.Z., Ahmed R., Khan M.M., Islam R.,
RA Rashid M.M., Khan S.A., Rahman M.S., Alam M.;
RT "Corchorus capsularis genome sequencing.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-
CC chain 3-oxoacyl-CoA + CO2 + CoA; Xref=Rhea:RHEA:32727,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57384, ChEBI:CHEBI:90725, ChEBI:CHEBI:90736;
CC EC=2.3.1.199; Evidence={ECO:0000256|ARBA:ARBA00001906};
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194, ECO:0000256|PIRNR:PIRNR036417}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|PIRNR:PIRNR036417}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMO89837.1}.
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DR EMBL; AWWV01008577; OMO89837.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R3J4T0; -.
DR STRING; 210143.A0A1R3J4T0; -.
DR EnsemblPlants; OMO89837; OMO89837; CCACVL1_07594.
DR Gramene; OMO89837; OMO89837; CCACVL1_07594.
DR OMA; ILAYECY; -.
DR OrthoDB; 930987at2759; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000188268; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009922; F:fatty acid elongase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR012392; 3-ktacl-CoA_syn.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR31561; 3-KETOACYL-COA SYNTHASE; 1.
DR PANTHER; PTHR31561:SF113; 3-KETOACYL-COA SYNTHASE 19-LIKE; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR PIRSF; PIRSF036417; 3-ktacl-CoA_syn; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|PIRNR:PIRNR036417};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000188268};
KW Transferase {ECO:0000256|PIRNR:PIRNR036417};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..307
FT /note="FAE"
FT /evidence="ECO:0000259|Pfam:PF08392"
FT DOMAIN 331..412
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
FT ACT_SITE 168
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 247
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 333
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 337
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 366
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 370
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
SQ SEQUENCE 454 AA; 50860 MW; A57CFDDCF5808D41 CRC64;
MELFMTICFI FLYCSIFFIC KLFLQRRNQC CYILAYECYK APEDQKLDTE TCGKLIMRNK
NLGLEEYRFL LQAMVNAGIG EETYGPRNVI SGTEESPTLP EALSEIDDIV FGTLDKLFAK
TGVSPSEIDI LVVTISMITS SPSIPARVIN RYKMREDVKV FNLTGMGCSA SVIAVDLVQN
LFKTYKNAFA LVVSSESLSP NWYCGKERSM MLPNILFRLG GCSLLLTNKR SLSNQAMLKL
KHSVRIHAGE SDEAYQSCTR IEDSQGYCGF FLTKSLPKAA AKAVAMNLRI LVPKMLPLRE
LARYAIVSYW RSKSKTAPEV AGAGLNLKTG VEHFCIHPGG RAVIDGMGRS LGLNEHDLEP
TRMALHRFGN TSAAGLWYVL SYMEAKKKLK KGDRILMISL GAGFKCNNCV WEVMKDLEDV
NVWEDCIGHY PVKSTSNTSF LEKYGWVNEP SKLN
//
