ID A0A1R3KNV2_9ROSI Unreviewed; 1554 AA.
AC A0A1R3KNV2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=GPI ethanolamine phosphate transferase 1 {ECO:0000256|ARBA:ARBA00020831};
GN ORFNames=COLO4_06141 {ECO:0000313|EMBL:OMP08762.1};
OS Corchorus olitorius.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Grewioideae; Apeibeae; Corchorus.
OX NCBI_TaxID=93759 {ECO:0000313|EMBL:OMP08762.1, ECO:0000313|Proteomes:UP000187203};
RN [1] {ECO:0000313|Proteomes:UP000187203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. O-4 {ECO:0000313|Proteomes:UP000187203};
RA Alam M., Haque M.S., Islam M.S., Emdad E.M., Islam M.M., Ahmed B.,
RA Halim A., Hossen Q.M.M., Hossain M.Z., Ahmed R., Khan M.M., Islam R.,
RA Rashid M.M., Khan S.A., Rahman M.S., Alam M., Yahiya A.S., Khan M.S.,
RA Azam M.S., Haque T., Lashkar M.Z.H., Akhand A.I., Morshed G., Roy S.,
RA Uddin K.S., Rabeya T., Hossain A.S., Chowdhury A., Snigdha A.R.,
RA Mortoza M.S., Matin S.A., Hoque S.M.E., Islam M.K., Roy D.K., Haider R.,
RA Moosa M.M., Elias S.M., Hasan A.M., Jahan S., Shafiuddin M., Mahmood N.,
RA Shommy N.S.;
RT "Corchorus olitorius genome sequencing.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
CC {ECO:0000256|ARBA:ARBA00008400}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMP08762.1}.
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DR EMBL; AWUE01012618; OMP08762.1; -; Genomic_DNA.
DR STRING; 93759.A0A1R3KNV2; -.
DR OrthoDB; 6598at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000187203; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16020; GPI_EPT_1; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR041266; EDS1_EP.
DR InterPro; IPR002921; Fungal_lipase-like.
DR InterPro; IPR007070; GPI_EtnP_transferase_1.
DR InterPro; IPR017852; GPI_EtnP_transferase_1_C.
DR InterPro; IPR037671; PIGN_N.
DR PANTHER; PTHR12250:SF0; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1; 1.
DR PANTHER; PTHR12250; PHOSPHATIDYLINOSITOL GLYCAN, CLASS N; 1.
DR Pfam; PF18117; EDS1_EP; 1.
DR Pfam; PF01764; Lipase_3; 1.
DR Pfam; PF04987; PigN; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000187203};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 718..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 857..879
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 891..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 930..948
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 479..953
FT /note="GPI ethanolamine phosphate transferase 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04987"
FT DOMAIN 1081..1172
FT /note="Fungal lipase-like"
FT /evidence="ECO:0000259|Pfam:PF01764"
FT DOMAIN 1322..1530
FT /note="EDS1 EP"
FT /evidence="ECO:0000259|Pfam:PF18117"
SQ SEQUENCE 1554 AA; 177081 MW; E9EED95BBAB72CF7 CRC64;
MGGDGILGNR DSKESKQIGR RRKWMKRREI WLVILGVILH AVYMLSIFDI YFKTPIVHGM
DLVTPRFSAP AKRLVLLVVI GGIADFWQNY VIAADGLRAD KFFEPDSEGN FRAPFLRSVI
KNQGRWGVSH ARPPTESRPG HVAIIAGFYE DPSAVTKGWK ANPVEFDSVF NRSRHTFSYG
SPDIVPIFCG ALPHSTWNTY PHEFEDFATD ASFLDEWSFE QFKSLLNKSN EDPKLKKLLQ
QDNLVIFLHL LGCDSNGHAH RPFSSIYLNN VKVVDHIAER VYNLLESYYK DNRTSYIFTA
DHGMSDKGSH GDGHPSNTDT PLVAWGAGIR YPKPTSGEDH SDHVLRFVDE HLHDTPTPKE
WGLDGIERVD VNQADIAPLM VSTLLGLPCP VNSVGSLPLG YVKLKEEEEV EAVVANTKQI
LNQFLRKSEI KRSHSLYFKP FKPLAEYSSM LNRIESLLSA RDYKAAMQLS ENLRSLALEG
LHYFQTYDWL MLMTMITLGY IGWMVFLVLH VLQAYTSLVG DIYKKEEPMR QKYNTGKVQF
LGCLFMGVLS ILLFLEHSPP LYHAYFAMTV FLWTQIFNEY QFIKALWRHL SGRKFNYVIK
LLAAAVVSVF ILELLVHSFT ERKLYTWCFL VVGAAASLYL YNLIPWNSGI PAFVLLTCWF
LSLFTLMPAE IPDNNKLVIA SGGMIILIGL AAKWVDLNAD WNTYWLAICK HKKKQPRFPM
LFLLQVILVG LSSVMVLLST SHRTEKQELH TIHQLMNWSI AGLSMVLPLF SDNGLLSRLN
SIFLGFAPTF LLLSIGYEAV FYGAFGLVLV AWILFENSLL YSSKVKKSSA ARKNLEEHIF
LENDVRYLQL SDLRIPLTFM VLFNVAFFGT GNFASIASFE ISSVYRFITV FSPFLMAALL
IFKLFIPFLL VICAFTAITK LLQVPRLGCY FLVILFSDVM TIHFFFLVKN TGSWMEIGNS
ISHFGIVSAQ VVFNSGSEIA NFVVSSGLLK VVWDKVWDSY GGVNLKEQQN LGLSLKWKVY
EEAKINIIVF VASPICTKSH LQEAELVPST ALKDPSFEFL CSNGNSFSID KAAITLFVSH
INELLQLKNQ YSRISKPLII TGHSLGGSVA SLFTLWLLES LDVTAAKHPL CLTFGSPLVG
DKGFQQAISE HPVWTSCFLH VAASEDPIPG LFITPHYLNN KGLSSQSIFY KPFGTFLLCC
ETGCSCSDNP EAVIELLKAM PLGKNSGNEE RLIVDYGRIV ENLESLIIFK GISQLNDFIP
TSLRAGTILQ LGAVGVHKSQ HQDYDLDNLI KLLEELEDIC FSSKRNVVDP AKKLNDIKLK
MAKLEWYKKV SKAQEKGYYD CYKNKPLRRD RDVEKYKRFL TDYWQEIVAQ TEKKPQTKHG
YFRIRWLYAG TAYRRMVEPL DIADYYESGQ KDYMTKGRSN HYIKMEQWLE EAEKQNGFSS
NAKKQSVDAI LTYDSCFWAH VEEARIWCKS LENADASATE KESSRKKLMK FEEYVMEQIK
KFAVSSEIFL KGSSFMQWWK EYEKIIGPDH HNLPLYDFMI NRKYKQYASG WCYV
//
