ID A0A1R3RSM1_ASPC5 Unreviewed; 1579 AA.
AC A0A1R3RSM1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=ASPCADRAFT_166367 {ECO:0000313|EMBL:OOF97468.1};
OS Aspergillus carbonarius (strain ITEM 5010).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=602072 {ECO:0000313|EMBL:OOF97468.1, ECO:0000313|Proteomes:UP000188318};
RN [1] {ECO:0000313|Proteomes:UP000188318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 5010 {ECO:0000313|Proteomes:UP000188318};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR EMBL; KV907497; OOF97468.1; -; Genomic_DNA.
DR STRING; 602072.A0A1R3RSM1; -.
DR VEuPathDB; FungiDB:ASPCADRAFT_166367; -.
DR OMA; CRDIRHH; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000188318; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000188318}.
FT DOMAIN 609..799
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 50..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1524..1579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1579 AA; 173539 MW; F5C474C4D0FF7591 CRC64;
MSSTPLPIAV DPVALVITEC ITVTSAMRKH ARWAHSSVSA ILGGGAVSRV YDRDTSAPPS
PRNGATPPRP RSRMSSADED HALANRWGLR GKKGKSMQDN PLISAFARLR SDLKGCRDIR
TFDAPALLHP FLQVIRSSST SAAITSLALV ALTKFFAYNI ISRDSLRLPM AMQLLSAAIT
HCRFEASDSA ADEIVLLRIL KLMEGMLSRP EGELLGDESV CEMMETGLSM CCQVRLSEVL
RRSAEMAMVN MCQVIFMRLS HLEISESDEL VSQLPMRSVS EQTHLKMDPS VDGDTVTSQH
PSAMGSDTGV TERERDSRDG SPDQTLNGNA VTAPPNPQDD TGDEVKPYSL PSIRELFRVL
IDLLDPHNHQ HTEPMKVMAL RIIDVALEVA GPSIAKHPSL AALAQDDLCR HLFQLVRSEN
IAILTGSLRV AGTLLLTCRP VLKLQQELYL SYLVACLHPK VEIPREPGIN PALYDGVPQV
PKLVKPSPSQ TNSGRSTPVP VKDRQKLGLE GGSRKPETRE AMVESIGVLA RIPSFMVELF
INYDCDVDRA DLCEDMIGLL SRSAFPDSAT WSTTNVPPLC LDALLGYVQF IYDRLDDEPV
SDGFPSIGQL RGQRRTKKLI IHAAQKFNEN PKAGIAYLAS HGIIENPDDP ALVARFLKGT
TRLSKKVLGE YLSKRSNEQL LDAFVELFDF AGKTIVDALR DLLGAFRLPG ESPLIERIVT
TFTEKYMQKA QPTQVADKDA LFVLTYGIIM LNTELYNPNI KSQNRMSCTA FARNLRGVNS
GQDFAPEFLE EIYDSIKHNE IILPDEHDNQ HAFDFAWREL LLKSSSAGEL VIGETNIYDA
EMFAATWKPV VSTLSYVFMS ASDDAVYSRV VTGFDQCAQI AARYGLTDAF DRIVFSLSSI
STLASEKPPS TTLNTEVQAG QKSVMVSELA VKFGRDFRAQ LAAVVLFRVL AGNEAAVQQS
WSHIVRILSN LFINSLIPAL DSSVNAELEI SPIPLQTPSQ VVDRDGRSTE TGLLSAFTSY
LSSYAADEPP EPSDEELENT LCTVDCITAC STDDILANIK SLPLESVAMV VEALLAQMPE
ESAPAVIVVK SERPSAGSRA SNGRTDGGKS NYDPGMMYLL EMATILTLRD SKTLETLGER
LLTTLQAFIR DARNVHSLAL SRIIHYLLNL LRLSHDQPYM RVPVILHGIS GFDQDILESV
AATTVNSLSR CISGPGLLRN EVTVSPDFWS ILQRLLQHKE AAPLVFDLLQ TIVESNPPII
TADNYESAIG LANEFISAGS VGYIEERQRD AHGRRVKGAK PFKSSENEVV ARGVKAIGFM
LHLTRRVPTL IQQSHLEESE AWSAYWSPIF QSLTAQCINP CRDIRHHAVS ALQRTLLSLE
ISSTEDQEWT AIFDQVLFPL IQRLLKPEVY HSDPVGMGET RVQVAILVCK IFLRYLDQLP
NRDSMLGLWL KILDILDRMM NSGQGDSLEE AIPESLKNIL LVMADGGYLV PPSQDPGKEP
VWTETKKRLE RFLPDLFKEI FPNVSDEKSA PVSTAPSPAP STPAEPEEHN SAEEPTATST
APAEAGADGA DGTAEENGP
//
