ID   A0A1R3UNP2_9ACTN        Unreviewed;       422 AA.
AC   A0A1R3UNP2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Bis(5'-nucleosyl)-tetraphosphatase (Asymmetrical) {ECO:0000313|EMBL:SIO87439.1};
DE            EC=3.6.1.17 {ECO:0000313|EMBL:SIO87439.1};
GN   ORFNames=BQ8420_16515 {ECO:0000313|EMBL:SIO87439.1};
OS   Nocardiopsis sp. JB363.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=1434837 {ECO:0000313|EMBL:SIO87439.1, ECO:0000313|Proteomes:UP000195722};
RN   [1] {ECO:0000313|EMBL:SIO87439.1, ECO:0000313|Proteomes:UP000195722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB363 {ECO:0000313|EMBL:SIO87439.1,
RC   ECO:0000313|Proteomes:UP000195722};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRFF01000105; SIO87439.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R3UNP2; -.
DR   Proteomes; UP000195722; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004081; F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448:SF0; RNASE ADAPTER PROTEIN RAPZ; 1.
DR   PANTHER; PTHR30448; UNCHARACTERIZED; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   Pfam; PF01230; HIT; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SIO87439.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195722}.
FT   DOMAIN          134..236
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   REGION          265..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           221..225
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00464"
FT   COMPBIAS        265..282
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   422 AA;  46382 MW;  06FE44F69D13C85F CRC64;
     MPPTPQVEIL TVGTRHGNPP TDHALLVDLT HRLRNPATDP ALRGLTGLDP ALAAHVLATP
     GAETVIRALA DQVLALTPHH PAPLRMVIQC HWGRHRSVAV AEEVALRLHA KDISVAVQHR
     DIDQPPLRRE DGCAFCDIAH GDAPAEIVRE WEEAIAIRPR SGGVDDDHVL ILPKVHVADA
     TVHPQTTGRV MVAAAEYAAQ VDANLNIITS KGESATQTVF HLHVHVVPRR PGDRLRLPWT
     PSWFDQVITF LRILGRHIRA PHNTEQGRLL DSHTRLEEQP AAPPREKGPV IYLGSGGPEG
     WWDGMRRFGP GYTPGPVQMR TTPEPWPHMD GTVATCPRCQ ARNNLSLLWL DSRPDLAHLM
     CPWCQSAWPD PEWSGTGPVA RVLQEPVTGG PGEQDEADIA PEVAYLTEYL RRMAGNTTPK
     AE
//