ID A0A1R3UNU7_9ACTN Unreviewed; 409 AA.
AC A0A1R3UNU7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=L-2-hydroxyglutarate oxidase {ECO:0000313|EMBL:SIO86232.1};
DE EC=1.1.3.15 {ECO:0000313|EMBL:SIO86232.1};
GN ORFNames=BQ8420_10955 {ECO:0000313|EMBL:SIO86232.1};
OS Nocardiopsis sp. JB363.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1434837 {ECO:0000313|EMBL:SIO86232.1, ECO:0000313|Proteomes:UP000195722};
RN [1] {ECO:0000313|EMBL:SIO86232.1, ECO:0000313|Proteomes:UP000195722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB363 {ECO:0000313|EMBL:SIO86232.1,
RC ECO:0000313|Proteomes:UP000195722};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the L2HGDH family.
CC {ECO:0000256|ARBA:ARBA00037941}.
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DR EMBL; FRFF01000072; SIO86232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R3UNU7; -.
DR OrthoDB; 9801699at2; -.
DR Proteomes; UP000195722; Unassembled WGS sequence.
DR GO; GO:0003973; F:(S)-2-hydroxy-acid oxidase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:SIO86232.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000195722}.
FT DOMAIN 7..397
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 409 AA; 44668 MW; F23F1C94A5CEEBF1 CRC64;
MRSTEHIGII GAGIVGLALA RHITLHRPGT RVTVLEKENR VAAHQTGHNS GVVHAGLYYR
PGSLKATLCR RGVGMLREYC AEHDLPYREA GKLLVAVNAE DEARLDDIEE RAKENGVPDV
TRLGPDGIRD IEPHAVGLAG LHSPTTAITD FVAVAEQLAD DVRRGGGRVL LNTPVLDLRQ
DDDGAEVLTG DPQGERIIHR FDRLVLCGGL HSDRLARMAG ADPDPRVVPF RGHYHEIVPE
RRDLVRGLLY PVPDPRYPFL GVHLTRHVHG EVMAGPNAIL ATALEGYRAR DLRARELGRT
LAWPGFWRLA RRHWTVGARE TVVSASRAVF AAQARRLLPE ITTADLRPAP AGVRAQALGR
DGSLLDDFHV DTHGRVVCVR NAPSPAATSS LAIAEFLYDS HVAGHRPSH
//
