ID A0A1R3URF6_9ACTN Unreviewed; 454 AA.
AC A0A1R3URF6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Phosphomannomutase {ECO:0000313|EMBL:SIO89497.1};
DE EC=5.4.2.8 {ECO:0000313|EMBL:SIO89497.1};
GN ORFNames=BQ8420_21885 {ECO:0000313|EMBL:SIO89497.1};
OS Nocardiopsis sp. JB363.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1434837 {ECO:0000313|EMBL:SIO89497.1, ECO:0000313|Proteomes:UP000195722};
RN [1] {ECO:0000313|EMBL:SIO89497.1, ECO:0000313|Proteomes:UP000195722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB363 {ECO:0000313|EMBL:SIO89497.1,
RC ECO:0000313|Proteomes:UP000195722};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; FRFF01000135; SIO89497.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R3URF6; -.
DR OrthoDB; 9803322at2; -.
DR Proteomes; UP000195722; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004615; F:phosphomannomutase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03089; PMM_PGM; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR005843; A-D-PHexomutase_C.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR PANTHER; PTHR43771; PHOSPHOMANNOMUTASE; 1.
DR PANTHER; PTHR43771:SF1; PHOSPHOMANNOMUTASE; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR Pfam; PF00408; PGM_PMM_IV; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SIO89497.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000195722}.
FT DOMAIN 7..129
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 158..256
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 265..370
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
FT DOMAIN 375..453
FT /note="Alpha-D-phosphohexomutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00408"
SQ SEQUENCE 454 AA; 48226 MW; 364FA34C7FFE744B CRC64;
MADLGSIFKA YDVRGVIPDT FNADIARAIG AAFARVVGGS SVVVAHDMRP SSPELTHAFA
EGVTSQGVDV VFAGLGSTDL LYYGSGALDM PGAMFTASHN PAEYNGIKMC RSGAAPISGE
SGLDDIRRLA EESLNGSGGL DHEGPKGSVT EKNLLPGYAE YLRGLVDLSV SRPLKAVVDA
GNGMGGHTVP AVLRDLPLEI VPLYFELDGT FPNHPANPLD PDNLVDLQAK VRETGADIGL
AFDGDADRCF VIDERGEPVP PSAVTALVAV QELKREPGAT VIHNLITSAA VPEIVTEHGG
KPLRTRVGHS FIKATMAETG AIFGGEHSAH YYFRDFWRAD TGMLAAMHVL RVLGADQRPL
SQITEEYSRY AASGEINSKV DDAPGRMAAV REAFIGRDGV TVDELDGLSV ALPEGAWFNL
RASNTEPLLR LNIEAADDTE VARLRDEVLD IVRA
//
