ID   A0A1R3UZE4_9ACTN        Unreviewed;       432 AA.
AC   A0A1R3UZE4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Prolidase {ECO:0000313|EMBL:SIO91102.1};
DE            EC=3.4.13.9 {ECO:0000313|EMBL:SIO91102.1};
GN   ORFNames=BQ8420_30050 {ECO:0000313|EMBL:SIO91102.1};
OS   Nocardiopsis sp. JB363.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=1434837 {ECO:0000313|EMBL:SIO91102.1, ECO:0000313|Proteomes:UP000195722};
RN   [1] {ECO:0000313|EMBL:SIO91102.1, ECO:0000313|Proteomes:UP000195722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB363 {ECO:0000313|EMBL:SIO91102.1,
RC   ECO:0000313|Proteomes:UP000195722};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRFF01000198; SIO91102.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R3UZE4; -.
DR   OrthoDB; 3514520at2; -.
DR   Proteomes; UP000195722; Unassembled WGS sequence.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0102009; F:proline dipeptidase activity; IEA:UniProtKB-EC.
DR   CDD; cd01299; Met_dep_hydrolase_A; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR43135; ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR43135:SF3; ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE; 1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 2.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Dipeptidase {ECO:0000313|EMBL:SIO91102.1};
KW   Hydrolase {ECO:0000313|EMBL:SIO91102.1};
KW   Protease {ECO:0000313|EMBL:SIO91102.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195722}.
FT   DOMAIN          68..422
FT                   /note="Amidohydrolase-related"
FT                   /evidence="ECO:0000259|Pfam:PF01979"
SQ   SEQUENCE   432 AA;  46403 MW;  6C9162E3A3AC4DCA CRC64;
     MNNNPESSHL VLKNVRVFDG ENDRLEPGHV VVCGRHIERI VPHTDTFAEP DGARVIDCAG
     EAGEITRVLM PGLIDAHTHL AVAGVSALEV LTGPDGLVHC KALVEARRML MRGFTSARDM
     GGPTTAIKNV IDSGDFPGPR IYPSNAAISQ TAGHGDFSAV YDAPTALGGP LSRADQVGIM
     RVADGTERVL AAVREQLKKG ASQVKLMAGG GVTSVYDDLD VVQFTPEELR VAVRAAEDWG
     TYVAVHVFTT EGIKRALDAG VRSIEHGQLA DEETVALIAS KGAWLSTQPF AEGDHTFPDP
     RSKEKDARVC QGVDHLFTWA RDHGARLAFG TDLLFAPDAG DRQSRMFARL DRYMSPVDAL
     RVGTSGNAAL LRMSGNRDPY GQAELGVVRP GAWADLLVVE GDPTKDLSLL ADPERNLSVI
     VKDGLTYRNR FG
//