ID A0A1R3WFB9_9MICO Unreviewed; 599 AA.
AC A0A1R3WFB9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Cell division protein FtsI (Penicillin-binding protein 3) {ECO:0000313|EMBL:SIT76819.1};
GN ORFNames=SAMN05880545_1651 {ECO:0000313|EMBL:SIT76819.1};
OS Microbacterium sp. RU33B.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1907390 {ECO:0000313|EMBL:SIT76819.1, ECO:0000313|Proteomes:UP000187047};
RN [1] {ECO:0000313|EMBL:SIT76819.1, ECO:0000313|Proteomes:UP000187047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU33B {ECO:0000313|EMBL:SIT76819.1,
RC ECO:0000313|Proteomes:UP000187047};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; FTPO01000001; SIT76819.1; -; Genomic_DNA.
DR RefSeq; WP_076680922.1; NZ_FTPO01000001.1.
DR AlphaFoldDB; A0A1R3WFB9; -.
DR STRING; 1907390.SAMN05880545_1651; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000187047; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:SIT76819.1};
KW Cell division {ECO:0000313|EMBL:SIT76819.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000187047};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 57..226
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..569
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 599 AA; 62731 MW; 81FF8773C6F614BB CRC64;
MTTRSTRSPR RRTVVALAVV LAVLAAFIVR LVDIQVVNAK EHIADSMENA LGSSRPIYGT
RGAIVDETGQ ILAGSILLYD AALDPRNISG YEAKGGFTRT VDGTTSLVPW AQATAEIAAV
TGQTAEEIAA IVTTAVAANA DTQWAQLAKG LSTEQYRTLA DLGIPYLSFT PHPARTYPDG
AVAGNLVGYM GTDGAALGGL EQSQDSCLQS TDGALSYQKG KDGVVIPGTE TEDPAVDGGT
LQLTINRDLQ WYLQQLIAEQ VVDQGALSGS IMVTEVATGK IRAAAEFPTV DPNDVAASKA
EDRGSRIFLN RFEPGSTFKA LTAATVIDAG GQTPLSTVTA SGRETFPNGA RVADSFGHPA
NRYTLTGVLI DSSNVGISKF AERVSAQTRY DYLTAFGIGQ GTSIPFNGQV TGNLPTTDRW
DNQSFYNIAF GQGVETTLAE LSGAYQAIAN DGLRVPLSLI EGCTRSDGTV VDADTSAPTQ
VVTPETAVQV QQMLANVATQ AGVAKAVAVP GYNVAEKTGT GEKSNGAGGY KSGVYFTTMV
GFAPAENPQY IVAVTLDEPT RIKSSGANAS AWQKAMTQVL KTYRVMPSTE AVPLLPKFG
//
