ID A0A1R3WJJ8_9RHOB Unreviewed; 391 AA.
AC A0A1R3WJJ8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:SIT78280.1};
GN ORFNames=SAMN05421849_0932 {ECO:0000313|EMBL:SIT78280.1};
OS Pontibaca methylaminivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Pontibaca.
OX NCBI_TaxID=515897 {ECO:0000313|EMBL:SIT78280.1, ECO:0000313|Proteomes:UP000192455};
RN [1] {ECO:0000313|EMBL:SIT78280.1, ECO:0000313|Proteomes:UP000192455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21219 {ECO:0000313|EMBL:SIT78280.1,
RC ECO:0000313|Proteomes:UP000192455};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FTPS01000001; SIT78280.1; -; Genomic_DNA.
DR RefSeq; WP_076648039.1; NZ_FTPS01000001.1.
DR AlphaFoldDB; A0A1R3WJJ8; -.
DR STRING; 515897.SAMN05421849_0932; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000192455; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000192455};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SIT78280.1}.
FT DOMAIN 4..260
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 347
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 377
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 391 AA; 40897 MW; BCFECCF078EA730B CRC64;
MTNVVIASAA RTGVGSFLGS FANTPAHDLG AAMLEAVVAR AGIDKSEVSE TILGQVLTAA
QGQNPARQAH IKAGLPQESA AWLVNQVCGS GLRSIALAAQ HIQLGDAEIV AAGGQENMSM
APHAANLRQG QKMGDLKYID TMIRDGLWDA FNGYHMGNTA ENVAGQWQIS REQQDEFAVA
SQNKAEAAQS AGKFKDEIVP FTIKTRKGDV VMESDEYIRH GANIEAMQKL RPAFTKEGTV
TAGNASGIND GAAGVLLMSA DNAEKRGIEP LARIVSYATV GLDPSIMGVG PIGASRKALE
KAGWKASDLD LVEANEAFAA QACAVNKDMG WDPEIVNVNG GSIAIGHPIG ASGARILNTL
LFELKRRNAK RGLATLCIGG GMGIALCVER P
//
