ID   A0A1R4B675_9VIBR        Unreviewed;       416 AA.
AC   A0A1R4B675;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Murein DD-endopeptidase MepM {ECO:0000313|EMBL:SJL84419.1};
DE            EC=3.4.24.- {ECO:0000313|EMBL:SJL84419.1};
GN   Name=mepM_2 {ECO:0000313|EMBL:SJL84419.1};
GN   ORFNames=VPAL9027_02403 {ECO:0000313|EMBL:SJL84419.1};
OS   Vibrio palustris.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1918946 {ECO:0000313|EMBL:SJL84419.1, ECO:0000313|Proteomes:UP000189475};
RN   [1] {ECO:0000313|EMBL:SJL84419.1, ECO:0000313|Proteomes:UP000189475}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 9027 {ECO:0000313|EMBL:SJL84419.1,
RC   ECO:0000313|Proteomes:UP000189475};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR   EMBL; FUFT01000005; SJL84419.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R4B675; -.
DR   STRING; 1918946.VPAL9027_02403; -.
DR   OrthoDB; 9805070at2; -.
DR   Proteomes; UP000189475; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd12797; M23_peptidase; 1.
DR   Gene3D; 3.10.450.350; -; 2.
DR   Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR   InterPro; IPR045834; Csd3_N2.
DR   InterPro; IPR011055; Dup_hybrid_motif.
DR   InterPro; IPR016047; Peptidase_M23.
DR   PANTHER; PTHR21666:SF291; MUREIN DD-ENDOPEPTIDASE MEPM; 1.
DR   PANTHER; PTHR21666; PEPTIDASE-RELATED; 1.
DR   Pfam; PF19425; Csd3_N2; 1.
DR   Pfam; PF01551; Peptidase_M23; 1.
DR   SUPFAM; SSF51261; Duplicated hybrid motif; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SJL84419.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189475};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          138..260
FT                   /note="Csd3-like second N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19425"
FT   DOMAIN          272..365
FT                   /note="Peptidase M23"
FT                   /evidence="ECO:0000259|Pfam:PF01551"
SQ   SEQUENCE   416 AA;  47557 MW;  7935C18D5FB9B889 CRC64;
     MTLLSSAFHD NGLHKQIKVT IPENQVVGSI LDKQLEQQKQ KQTQNIPDYE YTIKSGDNLS
     LIFSRLHFPY KDLMKVMETD LNYLKLDTLQ PGNTLRFWQT DDGKHLKKME LVFDIANSSS
     YTLNSDGGYD YHEVNLPGTW KNSTVIGEIH GSFSQSAHRA GLHIADIEQI VQLLKDKINF
     GRDLRAGDRF EVVQANQYVK GQLTGVREIK AIKIFNRKRV IAAYLNKDGQ YYDRHGESLQ
     KAFRRYPTKR RYRISSPYNP HRRHPITGRI MPHYGTDFAT PVGTPVLTTG DGVVTLIRDH
     PYAGLYVVVR HDSTYTTRYL HLSKIYVHRG QHVKRGQKIA LSGSTGRVTG PHLHYELIIK
     GHPVNAMKAK IPMARSVSKK DRQQFIHQRD RMDKLLAEKE ASLTHKSDAD DAGQDS
//