ID A0A1R4FVB1_9ACTO Unreviewed; 2176 AA.
AC A0A1R4FVB1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Fibronectin, type III domain protein {ECO:0000313|EMBL:SJM59859.1};
GN ORFNames=CZ771_11340 {ECO:0000313|EMBL:SJM59859.1};
OS Actinomycetales bacterium JB111.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales.
OX NCBI_TaxID=1434822 {ECO:0000313|EMBL:SJM59859.1, ECO:0000313|Proteomes:UP000196124};
RN [1] {ECO:0000313|EMBL:SJM59859.1, ECO:0000313|Proteomes:UP000196124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB111 {ECO:0000313|EMBL:SJM59859.1,
RC ECO:0000313|Proteomes:UP000196124};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FUHX01000066; SJM59859.1; -; Genomic_DNA.
DR Proteomes; UP000196124; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR040853; RapA2_cadherin-like.
DR NCBIfam; NF012211; tand_rpt_95; 1.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF9; TITIN; 1.
DR Pfam; PF17963; Big_9; 4.
DR Pfam; PF17803; Cadherin_4; 2.
DR Pfam; PF00041; fn3; 2.
DR SMART; SM00060; FN3; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 3.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000196124};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1602..1689
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1690..1780
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1782..1876
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1670..1708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1861..1887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2043..2062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..512
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2176 AA; 229147 MW; 2E0E2E873ED7DA0E CRC64;
MPPRRRRDHG SADDASQQRP TADTPTAPPP IDPADDVGAS PAPARTRAGS RPAPAAGSRP
AGTSGAGTSA AAASGEDRRE ARRHKRRRAV ASSTSLAVVA GAVVVAAFSY DGEPVADIEL
HDGGVWVTNS DELMVGRVNY PVQELDGSVT TASDEVDVLQ DGSTVFVVDS GAALLQTLDP
ATVSTGTGAV TIPRGADLQL GGGTIGMLDP STGALRAVPV EGANYLGDAE AEPAAHLGED
GQLAVGPDGR THGLSIDDAS VVTVEPGGVD DGSDAPGAPQ GGESASESAS ESPTTEPVAE
EGDQDEEEAS EQVRTRALAT TPDALDLAEQ VALTSVGDRS VVAVITEDND ELLVYVDDAE
PIDLTAYDLD LAEVAVQQPG ARSDEVVLAT RDALVHVPLD GGEPSIIRSP REGGPAQPIV
VGDCVHGAWD GADEGSYLLQ CGNGEPADAP IPLRGSDHAL RLRENHGLVV VNDTLTGTVY
LPQEDMQLVD NWDDTTPPDG ESEDETDSPD DRLEDVPPDR EEENRPPTAN PDSVGVRAGS
TTVVEVLAND TDPDGDLLTV TDVEDAGEQI GDISVIEGGR AVQITVPAEA TGRITVPYSI
TDGRENGESS STLTVEVVPD DVNSAPEVRE GREPRMDLAL GGTATIDVLS SMVDPEGDAM
VLESAETDSD DVVHFTPDGT LTFVDTGTSS GLKEVTVRVS DGSDTTEVTV PVEVRESTNL
PPRAVGDFIA VTEGEEVLLD VLANDVDPEG EPLRLGSVTT ADIVEVTPDY DTGQIHLEGL
TEGTAYLEYV VADAGGADAT GLVRVDVVAP DPDAAPIAVR DTALLPAGGT TLVDVLANDD
DPAGGLLAVQ QIDVPPDSPL VVSVIDHRLL RISAQTTPTG PQTLTYTVSN GSRSAVGEVT
VLPILADSAP QPPVAEPDVV DVRAGDYVTI PVLQNDSHPQ GMEFSLDPEL QEVPDGDRGH
FFTSGDVVRF RAPDTPQTVN AVYSITDENG NGASALITVR VQASSESNAA PIPEPIEVRA
FGGERIRIQV PVYGIDPDGD SVQLLGADTA PSLGRIVEIG PGYLDYEAYG QSSGTDTFSY
AVRDRLGAIG SAQIRVAVVP PPISNSRPQA QADSLEVRPG RTVDVDVLRN DTDADGDPLY
LADAPDGGPF DAMPELAPEA TEQHLIRITA PLTEGRYPLT YRASDRRGGI DSAVATVTVS
EDAPLLPPIA RDDLVAPADI IGHDVVTIPV LANDEDPDGT ADALTVELID VPEGARVTGN
NIQVPVLAER QVLTYRVEDP DGLEGFAFID IPGSESTAPV LRTNVRPIEV HSGELVEISI
YDYVVAPSGR PIRLTDTSQV TATNSDGGSP VVDATTLQFR SAEDYYGPAS ITFEVTDGIT
ARGSLSSRLT LPITVLSDGV NIPPTFRGGE MDVVPGEGEA ALNLRSAIDD PEDFSELRLD
FGEDGLPEGL EGRIEGHTLY VAADVDLAPG QTLDVPMTVS DPENDPVPSV IEVHVRPTDR
DVPSVPDVNI GEVEQGDTVA VDVLDGAFNP FEAEGEPLTI IGAQTERGTA TVDHSLSDVS
ITPGADHVGP VTVRVTVEDG TGLPTRRAEA RITMNVIGAP GRPTPPRVVD EQDSAVVLTW
PAPVSNGSPI TGYTVDTAGH RQVCATTTCT ITGLTNAQEY TFTVIATNAV GDSDPSAPSG
PAMPDVRPER PNAPEAERGD GSASLGWEVP ATRGTPVERY DVQVSPASGS GQISETSTAY
MWDGLTNGTS YTFRVRAYNQ ADEPSEWSPW SAPVVPAGPP TAPGEPQVQR VDSPIEAQIS
GSFGEAQGNG APVTGYEVII YQDGNEFSRF ETTGTSFTQD APEGHEYTVA VVAINEVGTG
PASPRSNSVR SFIKPTAPGR PTATATGTSR EITLDYSAAD PRGDEIVRYE VSTNGGEWRE
LEGDRITGLD NGSSYQFRVR ACNQYCGDPS PASATQIPYG PMGTPDLRLE YQEPTHWGDP
AQIDYGWGVP NGNGRPIVSA TVTTGLGTRR DGLAANGYTE NVEWDRTYQA TITVVRDLGN
GQTDSVTATA SEPVPAQPPR PERSVDIRFV RDGRDEPRQD CDDDNDQCRF LDFTWTNFGD
YWSQEGPYEV RWINVDDDDE LINSRPFWRN PDQFDFPQED GQYQSSRAVG ADITVRLEIR
NRDGDVVASD TYDIDP
//
