ID A0A1R4G6X4_9MICO Unreviewed; 709 AA.
AC A0A1R4G6X4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:SJM63825.1};
GN ORFNames=FM112_09480 {ECO:0000313|EMBL:SJM63825.1};
OS Gulosibacter sp. 10.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Gulosibacter.
OX NCBI_TaxID=1255570 {ECO:0000313|EMBL:SJM63825.1, ECO:0000313|Proteomes:UP000195931};
RN [1] {ECO:0000313|EMBL:SJM63825.1, ECO:0000313|Proteomes:UP000195931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10(10) {ECO:0000313|Proteomes:UP000195931};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR EMBL; FUIC01000024; SJM63825.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R4G6X4; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000195931; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SJM63825.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000195931}.
FT DOMAIN 47..222
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 248..393
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 709 AA; 76532 MW; 2543576FE6CF6E5C CRC64;
MEAQTTQDGQ GAAGAGESLH EAATRLLEQL TGSPDAELRS GQYEAIEALV ARRSRVLVVQ
RTGWGKSAVY FLAAKLMRQA GRGPALIVSP LLALMRDQVG AATRAGVVAR TLNSANAAEW
DAVHAELQAG VVDVLLVSPE RLTNPSFRDT VLPGLLDSIG MIVVDEAHCI SDWGHDFRPD
YRRIGAMIRE LPAQTPVLAT TATANSRVVA DVAEQLGEDT TVIRGPLARD SLRLGVAPTQ
APTARLAWLS EHLGDFWGSG IVYTLTVSAA QDTARALREA GWNVATYTGG TDPEERERLE
RALKDNELKA LVATSALGMG FDKPDLGFVV HLGAPSSPVA YYQQVGRAGR AADSADVLLL
PGPEDREIWE YFATASMPSE EDARAVLEAL DAEGTLSVPT LEARVGVRRS RLDLLLKTLS
VDGAVRRVRG GYKSTGAGWR YDAERYAHVA EVRRAEARAM LDYEAASTCR MRFLTEALDD
PDPRDCGRCD NCAGRWWDER VSEGASDRAR ELLDGVGLPI EVRGQWPTGM DHLGVALKGR
IPAEERAEEG RAIARFTDLG AGQRLREFLA ADAPDAPIPD DIGALCLRTL KDWPWTQRPD
CVIAVPSARR PVTVRSLAEG LAAAGRLEDL GDLRPLREHG GPDVNSAFRL RDLHAAFGLS
PEQAEAVRGR TVLLVDDVVV SRWTMTVCAR ELRLAGAAAV LPFALALRA
//
