ID A0A1R4HBA5_9GAMM Unreviewed; 1982 AA.
AC A0A1R4HBA5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
GN ORFNames=CRENPOLYSF1_440017 {ECO:0000313|EMBL:SJM93542.1};
OS Crenothrix polyspora.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Crenotrichaceae; Crenothrix.
OX NCBI_TaxID=360316 {ECO:0000313|EMBL:SJM93542.1, ECO:0000313|Proteomes:UP000195667};
RN [1] {ECO:0000313|EMBL:SJM93542.1, ECO:0000313|Proteomes:UP000195667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSM_CP1 {ECO:0000313|EMBL:SJM93542.1};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; FUKI01000120; SJM93542.1; -; Genomic_DNA.
DR Proteomes; UP000195667; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 1.
DR Gene3D; 2.60.40.3440; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 7.
DR InterPro; IPR006644; Cadg.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR025592; DUF4347.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003995; RTX_toxin_determinant-A.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF17963; Big_9; 1.
DR Pfam; PF14252; DUF4347; 1.
DR Pfam; PF05345; He_PIG; 1.
DR Pfam; PF00353; HemolysinCabind; 11.
DR PRINTS; PR00313; CABNDNGRPT.
DR PRINTS; PR01488; RTXTOXINA.
DR SMART; SM00112; CA; 1.
DR SMART; SM00736; CADG; 1.
DR SUPFAM; SSF51120; beta-Roll; 7.
DR SUPFAM; SSF49313; Cadherin-like; 1.
DR PROSITE; PS50268; CADHERIN_2; 2.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 9.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000195667};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 480..574
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 973..1074
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 253..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1982 AA; 203361 MW; 0CA0D8D1C0DA0662 CRC64;
MSNRIVFIDP RVSDYQSLIA DLPAGTEVVV LDANRDGVEQ IAQALQGKSN LDAIDIVSHG
ASGAVYLGSS ILDSYSIAGY ANQLADVGSH LGADGDILLY GCNVAAGDVG QAFINQLAQA
TGADVTASTN LTGHSALGGD WLLESSTGAI DAQSIQAAGF VGVLATTPTD GDDTITGTVN
NETIYALAGN DNVDGGAGDD FIYGDAGADT LKGNFGNDTL YGGIGNDTLD GGAGNDTLDG
GVDDDILKDY EGGSNTLSGG AGNDNISVNG DGGGTNNTLN GNEDNDTIYA QFWSNNNTVA
LNGGTGNDLI SLAFHGNSNN AEIDAGAGDD VIVVTPSIAG SIKITTGSGT DQIGLESAFR
ASPIIITDFS VTNTGNGIDK INLGNTANTN TNTGILTALE NWDGQDPFAG GFLRLVQNGV
DTLLQGDIDG KGTYNTWETL VTLQNTTASD FTAANFSPSY TPITVVINHA ATDITLSANS
VIENTAVGTG ILVGTINITD LDASGNSNVL TLTGTDASLF EIRNGVELFY TGSSPDFEDR
DSYNITATST DGTLTYSQNL TVNVTDVADD APNTWIGTEG NDNKVGTTDN DTLYGRSGND
VLDGGAGVDK LIGGFGNDTL KGNFGDDKLY GGAGNDNLQG GTGIDELHGG DENPNNDIYA
KELEWFHNAG DRLDGGFGDD TLYGDKGQDY LRGGAGKDVL YGGEDGDYLN GDAGDDALFG
DAGDDFITDN DGSNAFYGGD GNDVIGGTGD QNGGEGNDSL SGIGNGFTLD GGDGDDILFS
DATNSTLIGG AGNDRINLYL QDTLDATTND IIATLTTADA GVGDDVININ ISRNYSQGIS
QAKITTGAGA DTIELSNMTD SANKLGIITV SDFTVGSVVD HDKINLDVTD TGVLSALVGW
DGSANPFDAG FLRLVQNGAD TQLQWDKDGS ASSNNWTTLI TFEGKVASSF NADNFLPAYA
PRVVTNTAPT AVSLTNAIIA INENSDTSVP VKVADIQLTD DGAGTNTITL SGADAAKFEA
ISDALYLKAG VTLDYETQTA YNVNVSVTDK AVLGSTPVTT AYALAVNNVS DPANHVINGT
SGANTTLNGT AGDETINGLG NNDIINAGAG DDIVDGGTGN DTVHGGLGND SLIDWSGINT
LYGDEGNDNI SGIGNLYGGT GSDTVSPGAS TTITLGEGGT DLSVDVLSLF TYLGNAFGTT
QSAQASGIIV TDFKPGIGGD KVELNNQFDD LSLYLYGWDG VKNPFDDGYF RLMQNGADTE
LQLNWDGAAG GFGWQTLAIL KNTTATHFTG ANFSAGYTPV VASNHEPVAT PLSNQALLAN
TSLNYTLPSN AFVDPEGDAL IYTATLSDGT ALPSWLSFDK ATHTFSGIPA NSNAGTLNLS
ITASDTHGAS TSSPLSIKVS GVVNGVVQDG YVAGADLYVD TNNNGKADPS EKTGTKTDAN
GNFAFSSDLH GTIIAVGGTN TDTNLPNNLV IKGAEGSSVI NPITTLVQSY IEQHVGGTVQ
AAETAVKAAL GINAGIDLMH FDPLAPKNAA NPQAIELQKI VAQVVVLADL STNSSTSINN
LANVIATSQI PIDLTKIDVV TQILGTTKPN DTVINQIVNT NTAITHVTSI NQISQTQEDA
LNNVNDAPLA SNNKLSTPEN TAIESKLNAI DVDSNILTYT IVQNPTHGVV SLNTSGNFIY
TPAKDYVGAD VFSFKANDGQ LDSNTGTINL TIDNTNSAPV FTATANTLTV VSNSAINTVA
TNKGVTFTEA ALTHYFTDTD SASLGIKPLL LDTSLKATSN NSLPADTNAT GLITLVDDKV
LGGKFQMSAT DGVAVSSNVN VTYVDKVSSL LTAATVGDSI IVNAKTTAVK LMGGNGNDYL
IGNNGNDTLV GGAGNDVLIG GAGKDTFIFN TALSTTNVDT LTDFTSGIDK IQLSHTIFKG
FAINKGVGAI DVGLNSGNNK FIYEAATHTL YYDADGGAHN NAVTIAILGG SSVPVTTDFK
II
//
