ID A0A1R4J948_9MICO Unreviewed; 348 AA.
AC A0A1R4J948;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit {ECO:0000313|EMBL:SJN28499.1};
DE EC=1.2.4.4 {ECO:0000313|EMBL:SJN28499.1};
GN ORFNames=FM104_06075 {ECO:0000313|EMBL:SJN28499.1};
OS Microbacterium esteraromaticum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=57043 {ECO:0000313|EMBL:SJN28499.1, ECO:0000313|Proteomes:UP000196320};
RN [1] {ECO:0000313|EMBL:SJN28499.1, ECO:0000313|Proteomes:UP000196320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B Mb 05.01 {ECO:0000313|EMBL:SJN28499.1,
RC ECO:0000313|Proteomes:UP000196320};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; FUKO01000019; SJN28499.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R4J948; -.
DR OrthoDB; 3457658at2; -.
DR Proteomes; UP000196320; Unassembled WGS sequence.
DR GO; GO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:SJN28499.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000196320}.
FT DOMAIN 21..196
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 348 AA; 37338 MW; 605BEA5FAF400EA3 CRC64;
MTIAHDDVRL DTEPAPVTQA MTMAGALNRA LADALQADPE VVIFGEDVGA LGGVFRITDG
LTERFGEDRC FDTPLAESGI VGTAIGMAMN GMRPVVEMQF DAFALPAFEQ VVSHVAKFGN
RTRGAMRMPL VIRIPFAGGI GGVEHHCDSS EAYYAHTPGL TVVAPATPQD AYSMLRAAIS
SPDPVVFLEP KKLYWSKGEV DTSITADLGT ARIAREGTDV TVIAYAAMVP VALEAAEIAA
AEGRSVQVID VRSLAPFDDA TVTAAVRSTG RAVVVAEAPG YVSVASEIQA RVFERCFEYL
EAPVRRVTGF DTPFAPPKLE HWYLPDADRV LDAIDSLHWD DDVEQDAR
//
