ID   A0A1R4JHI6_9MICO        Unreviewed;       198 AA.
AC   A0A1R4JHI6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Na(+) H(+) antiporter subunit E {ECO:0000313|EMBL:SJN31452.1};
GN   ORFNames=FM119_07565 {ECO:0000313|EMBL:SJN31452.1};
OS   Mycetocola reblochoni REB411.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Mycetocola.
OX   NCBI_TaxID=1255698 {ECO:0000313|EMBL:SJN31452.1, ECO:0000313|Proteomes:UP000196778};
RN   [1] {ECO:0000313|Proteomes:UP000196778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EB411 {ECO:0000313|Proteomes:UP000196778};
RA   Dridi B.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC       family. {ECO:0000256|ARBA:ARBA00006228}.
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DR   EMBL; FUKR01000040; SJN31452.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1R4JHI6; -.
DR   OrthoDB; 3556991at2; -.
DR   Proteomes; UP000196778; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196778};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        38..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        67..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          171..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..192
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  22044 MW;  E0F61EE19213E6FF CRC64;
     MTTVSSRRRR VASYIVLLIG LALLWCLIWG SFSALTVLTG LILGLLVSVF FYLPAVELSG
     RVNVFRLVVF LLRILWDIMI ASMHITWMVI RPGFQTSNAI IAVQLHTRSD LILAWTAEAV
     SIVPGSIIVD QDRETSTLYI HAIDMSNEQD IDKLVRQVLA VERRMLLAVG SPSEAADARS
     RAREERAARA AARKGGQR
//