ID A0A1R4K7K9_9MICO Unreviewed; 496 AA.
AC A0A1R4K7K9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Xylulose kinase {ECO:0000256|RuleBase:RU364073};
DE Short=Xylulokinase {ECO:0000256|RuleBase:RU364073};
DE EC=2.7.1.17 {ECO:0000256|RuleBase:RU364073};
GN Name=xylB {ECO:0000256|RuleBase:RU364073};
GN ORFNames=FM104_10850 {ECO:0000313|EMBL:SJN40174.1};
OS Microbacterium esteraromaticum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=57043 {ECO:0000313|EMBL:SJN40174.1, ECO:0000313|Proteomes:UP000196320};
RN [1] {ECO:0000313|EMBL:SJN40174.1, ECO:0000313|Proteomes:UP000196320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B Mb 05.01 {ECO:0000313|EMBL:SJN40174.1,
RC ECO:0000313|Proteomes:UP000196320};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+);
CC Xref=Rhea:RHEA:10964, ChEBI:CHEBI:15378, ChEBI:CHEBI:17140,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57737, ChEBI:CHEBI:456216;
CC EC=2.7.1.17; Evidence={ECO:0000256|RuleBase:RU364073};
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|RuleBase:RU003733}.
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DR EMBL; FUKO01000023; SJN40174.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R4K7K9; -.
DR OrthoDB; 9782710at2; -.
DR Proteomes; UP000196320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004856; F:xylulokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0005997; P:xylulose metabolic process; IEA:InterPro.
DR CDD; cd07805; FGGY_XK_like_2; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR006000; Xylulokinase.
DR NCBIfam; TIGR01312; XylB; 1.
DR PANTHER; PTHR43095; SUGAR KINASE; 1.
DR PANTHER; PTHR43095:SF5; XYLULOSE KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU364073};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU364073};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:SJN40174.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU364073};
KW Reference proteome {ECO:0000313|Proteomes:UP000196320};
KW Transferase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:SJN40174.1};
KW Xylose metabolism {ECO:0000256|ARBA:ARBA00022629,
KW ECO:0000256|RuleBase:RU364073}.
FT DOMAIN 1..245
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 255..444
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 496 AA; 52970 MW; A400B0FA38355BC3 CRC64;
MIIAHDLGTT GNKASLHSDD GRLVASVTVP YPAHFAAGGV AEQNPQDWWD AVVRATRDLL
ARTETAPSEI TGLVVSGQMM GAVLLDADGE PARPAIIWAD TRSGAQQRQL EDALGAEHAY
RVLGHRLNPT YSVEKVMWVR DNEPDVWARV RRVCVAKDFI VQRLTGRLAT DRSDASGTNA
YDQLAGDWSD EVLSAARLDR SLFPEILEAT AIAGALTTTA AEALGLHTGV RVVMGGGDGP
MAAVGSGIVA PEDGAYVCLG TSSWISFAAN APLHDPQMRT FSFNNVVPNR FVPTATMQAG
GASVQWIAEA LSPDPARPET GRLTAEATED IDTEDLYFLP YLLGERSPIW DPDARGAFVG
LGRHHTRAHL MRAVLEGTAF NLLTGIHAFR ESGATIDRID AVGGGAQSDA YLSVLADVWG
VPVRRRTIVG EANSLGAAIT GAVGLGLAEF SAARALSEVT AEFTPDADRH ARYLTRHSRF
TDAYTALAPW FAGRPR
//
