ID A0A1S1NHQ7_9MYCO Unreviewed; 566 AA.
AC A0A1S1NHQ7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN Name=crtI_4 {ECO:0000313|EMBL:PQM45171.1};
GN ORFNames=BKN37_20795 {ECO:0000313|EMBL:OHU98344.1}, C1Y40_04658
GN {ECO:0000313|EMBL:PQM45171.1};
OS Mycobacterium talmoniae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1858794 {ECO:0000313|EMBL:OHU98344.1, ECO:0000313|Proteomes:UP000179734};
RN [1] {ECO:0000313|EMBL:OHU98344.1, ECO:0000313|Proteomes:UP000179734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MO-5499 {ECO:0000313|EMBL:OHU98344.1}, and NE-TNMC-100812
RC {ECO:0000313|Proteomes:UP000179734};
RA Greninger A.L., Elliott B., Vasireddy S., Vasireddy R.;
RT "Genome sequence of Mycobacterium talmonii.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PQM45171.1, ECO:0000313|Proteomes:UP000238296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2683 {ECO:0000313|EMBL:PQM45171.1,
RC ECO:0000313|Proteomes:UP000238296};
RX PubMed=28809146; DOI=10.1099/ijsem.0.001998;
RA Davidson R.M., DeGroote M.A., Marola J.L., Buss S., Jones V., McNeil M.R.,
RA Freifeld A.G., Elaine Epperson L., Hasan N.A., Jackson M., Iwen P.C.,
RA Salfinger M., Strong M.;
RT "Mycobacterium talmoniae sp. nov., a slowly growing mycobacterium isolated
RT from human respiratory samples.";
RL Int. J. Syst. Evol. Microbiol. 67:2640-2645(2017).
RN [3] {ECO:0000313|EMBL:PQM45171.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC BAA-2683 {ECO:0000313|EMBL:PQM45171.1};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC {ECO:0000256|ARBA:ARBA00038825}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHU98344.1}.
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DR EMBL; MLQM01000146; OHU98344.1; -; Genomic_DNA.
DR EMBL; PPEA01000662; PQM45171.1; -; Genomic_DNA.
DR RefSeq; WP_071028858.1; NZ_MLQM01000146.1.
DR AlphaFoldDB; A0A1S1NHQ7; -.
DR Proteomes; UP000179734; Unassembled WGS sequence.
DR Proteomes; UP000238296; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.660.50; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:PQM45171.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000179734}.
FT DOMAIN 21..323
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 566 AA; 61586 MW; F981236D0B2B200D CRC64;
MKDSSVPREA DVIVVGSGHN GLVAAAYLAK AGLDVLVVEA SPTAGGMTST NPFAPEAPEY
MINEASIQAS LFRTTTIDRD LGLSRYYGLR QTVIDPAHFQ LSADGASLGL WRDPRKTAAE
LAYFSKKDAR ALIELYEVID AAVEIGLPMM QTSVTQPEIK NILKSARALA KNRKQLSALG
RWMSSSQAEA VEESFEHDMI RAPMLSSLPF MPFDADMSGW SLIYLGVLSK YGVAMFHGGT
GSLPKALIGV IKDNHGDVIT RSPVEELIVT NNRCTGIRIK GGAEIHARRA VLTACSPRTT
LTRLLPRGVL EPKKQNAADH IPTRKRGIAD AKVNVALSGR IDMSKHEKWR DDGIDLRQAC
NCYHTYAQAL EAARACVRGQ VPDAIPGLAQ VTNSFDPSMS PPGKDLWWFW TGLTPSFPEE
GWDVARKKIT DSIIKDAEIY YKGVEDMQVA VRPLVLPDIE ERFWAIDGSV YHVDPTISRF
GPNKPVAGFA GYKTPVEGLY LTGSGTHPVA GISGMPGQNA ARIMLKHFKI QDKGGRLGAL
KDLLTTRKKA DVDPYSSGQN DPFPTG
//
