ID   A0A1S1QZX2_9ACTN        Unreviewed;      1307 AA.
AC   A0A1S1QZX2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Indolepyruvate ferredoxin oxidoreductase {ECO:0000313|EMBL:OHV39227.1};
GN   ORFNames=BCD49_11870 {ECO:0000313|EMBL:OHV39227.1};
OS   Pseudofrankia sp. EUN1h.
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC   Pseudofrankia.
OX   NCBI_TaxID=1834515 {ECO:0000313|EMBL:OHV39227.1, ECO:0000313|Proteomes:UP000179465};
RN   [1] {ECO:0000313|Proteomes:UP000179465}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EUN1h {ECO:0000313|Proteomes:UP000179465};
RA   Ghodhbane-Gtari F., Swanson E., Gueddou A., Morris K., Hezbri K., Ktari A.,
RA   Nouioui I., Abebe-Akele F., Thomas K., Gtari M., Tisa L.S.;
RT   "Sequence Frankia sp. strain EUN1h.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OHV39227.1}.
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DR   EMBL; MBLN01000042; OHV39227.1; -; Genomic_DNA.
DR   Proteomes; UP000179465; Unassembled WGS sequence.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   Gene3D; 3.40.50.970; -; 2.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR046667; DUF6537.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF20169; DUF6537; 1.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:OHV39227.1}.
FT   DOMAIN          717..748
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   REGION          112..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          417..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1307 AA;  135601 MW;  BB65CA06BCA95DBF CRC64;
     MTTQAGGPGA AGPGQAAPAP VAAEPALLSG VEALARLLVV RAELDARAGL TTATMVSGYP
     GSPLGTFDLT IERSAALLAE HRVRHRPGLN EELAAATVWG SQMGAGRSLL APRRDVAGPG
     EPPAASVPGD LAADAADGGT AAGGALGGDD GAIDGVVGAW YGKTPGLDRC GDVLKHAGAM
     GTGPNGGVVM FCGDDPSAKS STLACDSQYT FEDACVPVLV PGDQQDILDL GVHAFRMSRY
     SGAWTGLKIV TSVADGIGTV DAGVDRHTPS DPTGHAVDGQ PWRHIPSTAV GPHAAPGQEE
     QVIDLRLRAA EAYARHNRLD RVVGAPAGAR LGVVCAGKTY FDVAQALTDL GVGADRLADV
     GIRMLRLAVT YPLGRETVLE FARSVDEIVV IEEKRPFVET QLRAILHEAG LTTRVAGKRA
     TSQIGSADPA GTPRDGRPLV PMAGELDASK VAAVLKRVLP DLAAARVAAA TANGASNGAS
     NGAPNGSPNR RLLPVVTASA PRPVITLPLV DLPARPPGFC SGCPHNRSTV FPEGALVGGG
     VGCHGIMYFE ARHLGMKSLP PTPMGAEGVP WLGLSPFVDE PHLIQNLGDG TLSHSGILAI
     RASVAGGVNV TFKILYNTAV AMTGGQDVVG LMDVPAMTRA LEAEGVSRVV VCAEDPKHYG
     RRARFAPGVR VLGRDHLEEV QEELRSVPGV TVVIYDQRCA AESRRLRKRG LLPEPPRRVV
     INEAVCEGCG DCSVKSNCLS VLPHHTEFGE KRRVDDLSCN RDYTCLEGDC PSFVTITPRE
     PGLFARLRPG RSGTGSAGKK AAEHVRPHLP AGGLPEPDVQ PITESFGVYF TGVGGTGVVT
     ANRVIASAAQ AAGLAVGGLD QTGLSQKAGA VVSHLRLSPK RAGGLDAAAG ASTVGEGGAD
     LYLSGDILQA AAAKHLATVQ PGRTVAVVDV TVTPTAAMLQ RDIAAPDEAV MRAAIAERVG
     DGRALFLDSK RIAEQVFANQ LLGNIVLLGA AYQLGGLPLP LADLEKAMGR TGKAAADNRE
     AFAWGRWVAH DLAAVEAALA ATAGTDAGAG AGAGAVVATA TAKPSIFDPS PGAVATAGRL
     VAEGDLPAEL PDDLRALLVR RAAQAIDYQD AARATRFLGL VATAAGRDAA DHGWALTRAV
     AESWFKLLTY KDEYEVARLH LLADHAQTAA DLGIDGPYKV TYHLHPPSLR RMGLKHKLPA
     ARPWAVMFHG LRTMRRLRGT PFDIFGLDRD RRLERAVIKE YEALVTGNLT AGRPYADLVT
     LAESAQMIKG YESIKAAAVD RWRAQVAQLA PAEPAEPAEQ VTVGGNA
//