ID   A0A1S1V5T1_9FIRM        Unreviewed;       326 AA.
AC   A0A1S1V5T1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=HNH endonuclease {ECO:0000313|EMBL:OHW61775.1};
GN   ORFNames=EUAN_17780 {ECO:0000313|EMBL:OHW61775.1};
OS   Andreesenia angusta.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Gottschalkiaceae;
OC   Andreesenia.
OX   NCBI_TaxID=39480 {ECO:0000313|EMBL:OHW61775.1, ECO:0000313|Proteomes:UP000180254};
RN   [1] {ECO:0000313|EMBL:OHW61775.1, ECO:0000313|Proteomes:UP000180254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1989 {ECO:0000313|EMBL:OHW61775.1,
RC   ECO:0000313|Proteomes:UP000180254};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Eubacterium angustum.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OHW61775.1}.
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DR   EMBL; MKIE01000007; OHW61775.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S1V5T1; -.
DR   STRING; 39480.EUAN_17780; -.
DR   Proteomes; UP000180254; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   Gene3D; 1.10.30.50; -; 1.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   InterPro; IPR047693; RNA-guided_IscB-like.
DR   InterPro; IPR025938; RRXRR_dom.
DR   NCBIfam; NF040563; guided_IscB; 1.
DR   Pfam; PF01844; HNH; 1.
DR   Pfam; PF14239; RRXRR; 1.
DR   SMART; SM00507; HNHc; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:OHW61775.1};
KW   Hydrolase {ECO:0000313|EMBL:OHW61775.1};
KW   Nuclease {ECO:0000313|EMBL:OHW61775.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000180254}.
FT   DOMAIN          108..159
FT                   /note="HNH nuclease"
FT                   /evidence="ECO:0000259|SMART:SM00507"
FT   REGION          31..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  38305 MW;  DBDA04C5E24202C9 CRC64;
     MFKGTIQLRQ DVKHLMDVRR GYRRYKRSHK RYRPARFDNR ASSKRKSRIA PSIKQKKDSI
     LRVVNKLDKI TPISNIVLED VAIDIRAMTE GYKPYRWQYQ KSNRLDENLR KAAILRDGNR
     CMMCGKTNCI LEVHHIQPRR LKGSDTLGNL ITLCSGCHEK VSDEELNYQN YFYSLINGKN
     TRFDYAQHVM QGKTYLREEL SKIAPLEHTV GGDTSNRRID WDIEKSHSND ALCITGLQPS
     STDVKDWNIK PMRRKSKAKT ESLNEFKHRD IVRYTKKTGE SYVGYITALY PEKNQCNITT
     LEGKVLKRYG IKSLDIVWRF SRIYWT
//