ID A0A1S2AU10_9GAMM Unreviewed; 150 AA.
AC A0A1S2AU10; A0A379YKP1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Transcriptional repressor NrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN Name=nrdR {ECO:0000256|HAMAP-Rule:MF_00440,
GN ECO:0000313|EMBL:SUI46430.1};
GN ORFNames=E1N14_006450 {ECO:0000313|EMBL:QTE79264.1}, E1N14_13865
GN {ECO:0000313|EMBL:KAB7509628.1}, NCTC10738_00182
GN {ECO:0000313|EMBL:SUI46430.1};
OS Shewanella algae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=38313 {ECO:0000313|EMBL:SUI46430.1, ECO:0000313|Proteomes:UP000254069};
RN [1] {ECO:0000313|EMBL:SUI46430.1, ECO:0000313|Proteomes:UP000254069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10738 {ECO:0000313|EMBL:SUI46430.1,
RC ECO:0000313|Proteomes:UP000254069};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAB7509628.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5071 {ECO:0000313|EMBL:KAB7509628.1};
RA Thorell K., Rodriguez J.M., Sjoling A.;
RT "Resequencing of Shewanella algae Type Strain.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QTE79264.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CECT 5071 {ECO:0000313|EMBL:QTE79264.1};
RA Martin-Rodriguez A.J.;
RT "Comparative genomics of Shewanella algae.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes. {ECO:0000256|HAMAP-Rule:MF_00440}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00440};
CC Note=Binds 1 zinc ion. {ECO:0000256|HAMAP-Rule:MF_00440};
CC -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000256|HAMAP-
CC Rule:MF_00440}.
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DR EMBL; SMNR01000019; KAB7509628.1; -; Genomic_DNA.
DR EMBL; CP068230; QTE79264.1; -; Genomic_DNA.
DR EMBL; UGYO01000001; SUI46430.1; -; Genomic_DNA.
DR RefSeq; WP_025009434.1; NZ_UGYO01000001.1.
DR STRING; 38313.GCA_000947195_01293; -.
DR GeneID; 72198981; -.
DR KEGG; salg:BS332_13840; -.
DR OrthoDB; 9807461at2; -.
DR Proteomes; UP000254069; Unassembled WGS sequence.
DR Proteomes; UP000325940; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00440; NrdR; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003796; RNR_NrdR-like.
DR NCBIfam; TIGR00244; transcriptional regulator NrdR; 1.
DR PANTHER; PTHR30455; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR PANTHER; PTHR30455:SF2; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Metal-binding {ECO:0000256|HAMAP-Rule:MF_00440};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Reference proteome {ECO:0000313|Proteomes:UP000254069};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|HAMAP-Rule:MF_00440};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Zinc {ECO:0000256|HAMAP-Rule:MF_00440};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|HAMAP-
KW Rule:MF_00440}.
FT DOMAIN 49..139
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT ZN_FING 3..34
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00440"
SQ SEQUENCE 150 AA; 17182 MW; 92C19C4BA8FF571F CRC64;
MHCPFCSATD TKVIDSRLVA DGHQVRRRRE CTLCHERFTT FEGAELVMPR VIKRDGSRQP
FDEDKLRGGM LRAAEKRPVS MDKIEEAISK IKSTLRATGE REVTSEMIGN LMMDHLIELD
KVAYIRFASV YRAFEDVSEF GEAIAKLEKK
//
