ID A0A1S2DIP9_9GAMM Unreviewed; 352 AA.
AC A0A1S2DIP9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=BC443_02810 {ECO:0000313|EMBL:OHZ03833.1};
OS Salinicola sp. MIT1003.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Salinicola.
OX NCBI_TaxID=1882734 {ECO:0000313|EMBL:OHZ03833.1, ECO:0000313|Proteomes:UP000179615};
RN [1] {ECO:0000313|EMBL:OHZ03833.1, ECO:0000313|Proteomes:UP000179615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT1003 {ECO:0000313|EMBL:OHZ03833.1,
RC ECO:0000313|Proteomes:UP000179615};
RA Biller S.;
RT "Membrane vesicles in seawater: heterogeneous DNA content and implications
RT for viral abundance estimates.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHZ03833.1}.
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DR EMBL; MCAP01000006; OHZ03833.1; -; Genomic_DNA.
DR RefSeq; WP_071230364.1; NZ_MCAP01000006.1.
DR AlphaFoldDB; A0A1S2DIP9; -.
DR STRING; 1882734.BC443_02810; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000179615; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000179615}.
FT DOMAIN 22..190
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 216..336
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 352 AA; 39455 MW; C2BCEAA024ECB75D CRC64;
MKVFPDKLED ALKKRLPPVV MVAGDEPLIH LEACDAVRRV ARERGIEERE VMHVESGFQW
TQLLESASSL SLFASSKLIE VRLGGQSPGQ DGGKALEAYA EQAGDSDNVL LLSSQRLDRK
AQSSKWFKTL DKLGVFVPVW PVDHQRLGFW MRDRANRYGF TMDMDAARLL GERTEGNLLA
ADQELQKLAL LMPPNARLDV SAIANGVESS ARYDVFTLTD ACLKGDRDRV ARIVRGLRQE
GVEAPVILWA LTRELRTLLS IFQHLDQGQS LEHACKAQRP MIPEKRRPGY QQALKRLPQR
RLHKLLLFAQ RIDLAIKGAV ALPVWDCLQD LALTLAGGRG LLAEMPYAYR TA
//
