ID   A0A1S2I299_9MICO        Unreviewed;       528 AA.
AC   A0A1S2I299;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Glycosyl transferase family 2 {ECO:0000313|EMBL:OII18280.1};
GN   ORFNames=BIV00_09295 {ECO:0000313|EMBL:OII18280.1};
OS   Curtobacterium sp. MCBA15_012.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Curtobacterium.
OX   NCBI_TaxID=1898738 {ECO:0000313|EMBL:OII18280.1};
RN   [1] {ECO:0000313|EMBL:OII18280.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCBA15_012 {ECO:0000313|EMBL:OII18280.1};
RA   Chase A.B., Arevalo P., Polz M.F., Berlemont R., Martiny J.B.;
RT   "Evidence for ecological flexibility in the cosmopolitan genus
RT   Curtobacterium.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OII18280.1}.
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DR   EMBL; MJGP01000013; OII18280.1; -; Genomic_DNA.
DR   RefSeq; WP_065959359.1; NZ_CP126267.1.
DR   AlphaFoldDB; A0A1S2I299; -.
DR   STRING; 1898738.BIV00_09295; -.
DR   OrthoDB; 9763050at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd06434; GT2_HAS; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR22913; HYALURONAN SYNTHASE; 1.
DR   PANTHER; PTHR22913:SF12; N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR   Pfam; PF13641; Glyco_tranf_2_3; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000313|EMBL:OII18280.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        508..527
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          415..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   528 AA;  58582 MW;  F144D2FEB09C5C14 CRC64;
     MFTFILQIRQ MVEGHPEFYL FAVYSAVIWL LWILKVVLSA RYRPFTGTYT GTTSVVVPVV
     DEPLDLFRDV IGRMVEQRPG EIIVVINGAR NEALEEVCDE FAPLVRWTHT PIPGKRNAVK
     VGTELSNGDI TVLVDSDTVW TPGTLEELLK PFADESVGGV TTRQRILEPT RSWITRWADW
     LENSRALYSM PAQSVLGQIG CLPGRTIAFR RSILTRVMDK FMHEEFMGVF LEVSDDRTLT
     NLTLKEGYRT VYQYTSLVYT DAPLQVKKLF KQQLRWARGS QYNTLRMLPW MLGHAPLLAV
     FFVTDILLPF MLFGVIAGWI YRALTGQGEN LYQGILQQYG FSTGFVYVAA LMVVSSVLSM
     AIRQIRHLSE KPSDFFRLPL FIIVSTFFLM PIRLIGFFRL AHASGWGTRA GAYAGGPMEQ
     EPVQPTTGLA PVSPVDAAGT GDGPATGAAD RALPAEQAAA DRAFDELFGA DATTTSTTTV
     LATRRSTATA AAPAGRPAPR RGRRLNPYAA IPYCIGIAIF ALEAFLIV
//