ID A0A1S2LAD6_9BACI Unreviewed; 688 AA.
AC A0A1S2LAD6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=RND transporter {ECO:0000313|EMBL:OIJ09371.1};
GN ORFNames=BKP35_17055 {ECO:0000313|EMBL:OIJ09371.1};
OS Anaerobacillus arseniciselenatis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anaerobacillus.
OX NCBI_TaxID=85682 {ECO:0000313|EMBL:OIJ09371.1, ECO:0000313|Proteomes:UP000180098};
RN [1] {ECO:0000313|EMBL:OIJ09371.1, ECO:0000313|Proteomes:UP000180098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15340 {ECO:0000313|EMBL:OIJ09371.1,
RC ECO:0000313|Proteomes:UP000180098};
RA Bassil N.M., Lloyd J.R.;
RT "Draft genome sequences of four alkaliphilic bacteria belonging to the
RT Anaerobacillus genus.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ09371.1}.
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DR EMBL; MLQQ01000045; OIJ09371.1; -; Genomic_DNA.
DR RefSeq; WP_071314580.1; NZ_MLQQ01000045.1.
DR AlphaFoldDB; A0A1S2LAD6; -.
DR OrthoDB; 9782006at2; -.
DR Proteomes; UP000180098; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000180098};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..322
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 521..667
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 688 AA; 75929 MW; A92E0B14CEF496A3 CRC64;
MSDIARKIIK YKKPIVIIFM ILTVVSAIAQ FFVSVNYNMS DYMPEDAPST KAIEVMEEEF
DRSLANAQVM IQDVSLQEAL LYKELLAEID GVSDVVWLDE VIDLKIPIEM IEKDLVESYY
KENNALFSLT IREGDEVAVT DAIYELIGDE NALAGEAVDT AVSQKMAFSE SLYAALLLVP
LIVIILILST TSWIEPVFFL TAIGVSVIIN LGTNIFVGEV SFVTQSVAPI LQLAVSLDYA
VFLLHSFSDY RKQTNNPEEA MQLAIKKSFP AISASAATTF FGFMALTFMQ FEIGADLGIN
LLKGIVLSFI SVMVFLPALT VLFYKWIDKT QHRSFVPSFN SVGKSAMKVR VLSLLIVFLV
IVPSYLAQKE TTFIYGIGEQ PETTRLGSDI VAIDEVFGTS TPIVLLVPKG DVAREVSLEQ
DLEKIDRVTS LISYNQSVSP AIPPEYLDES ITEQFHSENY SQIILFTNTE SEGDVAFNVV
ETVLDIAASY YGEEFFALGE SVSLYDMKTT VLKDNTVVNT LTVVAIATVL LFTFKSISIP
VVLLLTIQAS VWINLAVPYF TETPLVFVGY LVVGTVQLAA TVDYAILFTE NYLENRKEMT
ARESIVKTLN EKTFSISISA AILSSVGFIL WITSTNPIVA SIGLLLGRGA LLAFVMVLFF
LPAVLIVFDK VIGKTTLKAK FFKGENAK
//
