ID A0A1S2P8M1_9ACTN Unreviewed; 406 AA.
AC A0A1S2P8M1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:OIJ89805.1};
GN ORFNames=BIV24_18775 {ECO:0000313|EMBL:OIJ89805.1};
OS Streptomyces colonosanans.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428652 {ECO:0000313|EMBL:OIJ89805.1, ECO:0000313|Proteomes:UP000179935};
RN [1] {ECO:0000313|EMBL:OIJ89805.1, ECO:0000313|Proteomes:UP000179935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC 93 {ECO:0000313|EMBL:OIJ89805.1,
RC ECO:0000313|Proteomes:UP000179935};
RA Lee L.-H., Ser H.-L., Law J.W.-F.;
RT "Genome sequence of Streptomyces sp. MUSC 93.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ89805.1}.
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DR EMBL; MLYP01000049; OIJ89805.1; -; Genomic_DNA.
DR RefSeq; WP_071367637.1; NZ_MLYP01000049.1.
DR AlphaFoldDB; A0A1S2P8M1; -.
DR STRING; 1428652.BIV24_18775; -.
DR OrthoDB; 9774495at2; -.
DR Proteomes; UP000179935; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000179935}.
FT DOMAIN 81..313
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 44261 MW; DB1AACFF19304884 CRC64;
MAQTTGRDEE RSARKPGGPD AEQPVSATEG LLRLRREHRI AAYRRAERVL ARPGFLGTLR
ERLALLEDAQ DVYDLDETGD VYGNGVVEAL EEKVAGLLGK EAAAFFPTGT MAQQVALRCW
AGRTGNTTVA LHALAHPEVH ERKAFSQVSG LRPVRVTSEP RLPTADEVRG FEEPFGALML
ELPLRDAGFV LPSFEELTEI VQAARERDAV VHFDGARLWE TTVHFGRPLD EIADLADSVY
VSFYKSLDGY GGAALAGPAT LVQEAKAWRH RYGGLAFQQF PTALSALAGL ERELPRLPEY
VRHARVVAAA LREGFAAAGV PWAHVHPEEP HTHEFRVWLP YDADVLGQAA VQQAEETGTL
LFANPWDVGG PGLAFTEISV KAHGLAWTAD DVKVAVTEFV GRLPGA
//
