ID A0A1S2P9L7_9ACTN Unreviewed; 540 AA.
AC A0A1S2P9L7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=BIV23_40200 {ECO:0000313|EMBL:OIJ90483.1};
OS Streptomyces monashensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1678012 {ECO:0000313|EMBL:OIJ90483.1, ECO:0000313|Proteomes:UP000179642};
RN [1] {ECO:0000313|EMBL:OIJ90483.1, ECO:0000313|Proteomes:UP000179642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC 1 {ECO:0000313|EMBL:OIJ90483.1,
RC ECO:0000313|Proteomes:UP000179642};
RA Lee L.-H., Ser H.-L., Law J.W.-F.;
RT "Genome sequence of Streptomyces sp. MUSC 1.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ90483.1}.
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DR EMBL; MLYO01000089; OIJ90483.1; -; Genomic_DNA.
DR RefSeq; WP_071385944.1; NZ_MLYO01000089.1.
DR AlphaFoldDB; A0A1S2P9L7; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000179642; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000179642};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..43
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 44..540
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010327805"
FT DOMAIN 52..179
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 183..502
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 346
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 540 AA; 58201 MW; F56E10E5A94D7175 CRC64;
MRRNHSTTPR TPRLPGSSRV FGSLLLVAAA GVLTLGAAPS ARAAVPPTPL DRVIPAPASV
QPGGTPYRLA RGTSVRVDAT PEVRRIGAYL AGILRPSTGY RLPLTESGTA GIRLHLAKGD
YGAEGYRLHS GADGVTLTAS APAGLFHGVQ TLRQLLPAAV EKRTVQPGPW QIAGGTVTDR
PRYAYRGAML DVSRHFFTVA QVERYIDELA LYKVDELHLH LSDDQGWRIA IDSWPRLATY
GGSTEVGGGK GGYYTKAEYR EIVRYAASRY LEVVPEIDMP GHTNAALASY APLNCNGEAP
PLYTGTKVGF SSLCAAKQVT YDFADDVLRE LAALTPGRYL HIGGDEAHST SHADYVTIMD
RVQPLVGKYG KTVIGWHQLT GAHPVKGAIA QYWGLDSTSA ADKDQVVQAA RNGTGLILSP
ADRVYLDMKY TKDTKPGLDW AGLVEVRRSY DWDPGNYLAG APGSAVRGVE APLWSETLKT
SADIDYMAFP RLPGAAELGW SPAVTHDWDA YKVRLAAQAP RWDALGIGYY RSPQVPWPAA
//
