ID A0A1S2QD25_9ACTN Unreviewed; 341 AA.
AC A0A1S2QD25;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:OIK03531.1};
GN ORFNames=BIV23_21835 {ECO:0000313|EMBL:OIK03531.1};
OS Streptomyces monashensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1678012 {ECO:0000313|EMBL:OIK03531.1, ECO:0000313|Proteomes:UP000179642};
RN [1] {ECO:0000313|EMBL:OIK03531.1, ECO:0000313|Proteomes:UP000179642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC 1 {ECO:0000313|EMBL:OIK03531.1,
RC ECO:0000313|Proteomes:UP000179642};
RA Lee L.-H., Ser H.-L., Law J.W.-F.;
RT "Genome sequence of Streptomyces sp. MUSC 1.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIK03531.1}.
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DR EMBL; MLYO01000035; OIK03531.1; -; Genomic_DNA.
DR RefSeq; WP_071382602.1; NZ_MLYO01000035.1.
DR AlphaFoldDB; A0A1S2QD25; -.
DR OrthoDB; 2971563at2; -.
DR Proteomes; UP000179642; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23131; ENDORIBONUCLEASE LACTB2; 1.
DR PANTHER; PTHR23131:SF0; ENDORIBONUCLEASE LACTB2; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OIK03531.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000179642}.
FT DOMAIN 25..251
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 130..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 37172 MW; 403F1DE040E148B9 CRC64;
MATTFDHGGG VRSVAVPIPD NPLGHTLVHV VETDRGPVLV DTGWDDPGSW DTLVAGLAAC
RTTVGEVYGV VVTHHHPDHH GLSARVREAS GAWVALHPAD AAIVRRTRET RPERWYTYMA
AKLTAAGAPE EHVAPLRTPR PRSLPGLSPA LPDREIVPGE LLDLPGRRLR AIWTPGHTPG
HVCLHLEEEH PARLAGHGRL FSGDHLLPGI TPHIGLYEDP DDTTVTDPLG DYLDSLERIG
RLVPAEVLPA HQHAFTDAPG RVRELLAHHE ERLAGLLALL AEPLTPWQVA ERMEWNRPWG
QIPYGSRNIA VSEAEAHLRR LVKQGRAEAV TGSEPVAYVA V
//
