ID A0A1S2XD32_CICAR Unreviewed; 518 AA.
AC A0A1S2XD32;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=E3 ubiquitin-protein ligase dbl4-like {ECO:0000313|RefSeq:XP_004486428.1};
GN Name=LOC101515147 {ECO:0000313|RefSeq:XP_004486428.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004486428.1};
RN [1] {ECO:0000313|RefSeq:XP_004486428.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004486428.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
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DR RefSeq; XP_004486428.1; XM_004486371.3.
DR AlphaFoldDB; A0A1S2XD32; -.
DR STRING; 3827.A0A1S2XD32; -.
DR PaxDb; 3827-XP_004486428-1; -.
DR GeneID; 101515147; -.
DR KEGG; cam:101515147; -.
DR eggNOG; KOG1812; Eukaryota.
DR OrthoDB; 2943236at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000087171; Chromosome Ca1.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd22582; BRcat_RBR_unk; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF466; RING_U-BOX SUPERFAMILY PROTEIN; 1.
DR Pfam; PF01485; IBR; 2.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 207..425
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 211..255
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 21..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 59902 MW; CA8BCE43A1D95ACB CRC64;
MEDQDVLGYR TFVDVEREEE EEEDEFCSCC EDEKEDEERE EEEWKEIEET VVEGLKEELD
EFSVKMFFKG LSITGVENST SGFSGIGVFM ERSSSFPPIR VQKRLDFYAE EPMVDYLALM
DGLLEAMQNK IRRVYAFTDS ELLYKITFDE NLDMPLLMAL RERILEHANN FETFDLKLVP
SIDLEQPMQL AKVAMGLVTF PVNGERLLEN CSICCDDKPV PMMITLKCSH TFCSHCLRSY
ADSKVQCCQV PTRCPQPGCR YCISAPECKS FLPFASFESL EKTLTEANIV ESDRIYCPFP
NCSVVLDPCE CLLANDGSSS QSDNSCIECP VCKRFICVDC GVPWHSSVTC EEYQSLPEEE
RDASDITLHR LAQDKRWKRC QQCRRMIELT QGCYHMTCWC GHEFCYSCGA EYREGQQTCQ
CAYWDEDSLT HSLQESEQWA WETSLIMDAY SDQERSQLAL IQRFLDGGFS LSDHNPYQSP
PPHCTESFVD PLKDLHQLPW LERFVSVISD NYYEDYMQ
//
