ID A0A1S2XPA2_CICAR Unreviewed; 344 AA.
AC A0A1S2XPA2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Phosphatidylinositol:ceramide inositolphosphotransferase 2 isoform X1 {ECO:0000313|RefSeq:XP_004492387.1};
DE SubName: Full=Phosphatidylinositol:ceramide inositolphosphotransferase 2 isoform X2 {ECO:0000313|RefSeq:XP_004492388.1};
GN Name=LOC101492499 {ECO:0000313|RefSeq:XP_004492387.1,
GN ECO:0000313|RefSeq:XP_004492388.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004492387.1};
RN [1] {ECO:0000313|RefSeq:XP_004492387.1, ECO:0000313|RefSeq:XP_004492388.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004492387.1,
RC ECO:0000313|RefSeq:XP_004492388.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC {ECO:0000256|ARBA:ARBA00005441}.
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DR RefSeq; XP_004492387.1; XM_004492330.3.
DR RefSeq; XP_004492388.1; XM_004492331.3.
DR STRING; 3827.A0A1S2XPA2; -.
DR PaxDb; 3827-XP_004492388-1; -.
DR GeneID; 101492499; -.
DR KEGG; cam:101492499; -.
DR eggNOG; KOG3058; Eukaryota.
DR OrthoDB; 67418at2759; -.
DR Proteomes; UP000087171; Chromosome Ca3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR045221; Sphingomyelin_synth-like.
DR InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR PANTHER; PTHR21290:SF54; PLANT INOSITOL PHOSPHORYLCERAMIDE SYNTHASE; 1.
DR PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR Pfam; PF14360; PAP2_C; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 202..270
FT /note="Sphingomyelin synthase-like"
FT /evidence="ECO:0000259|Pfam:PF14360"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 39103 MW; FC506B9E3F4B4929 CRC64;
MESSRYSVTT TASSTTSSSS TITTYNNKKN MSLYIGREAS KLWKRVCAET TTEINLLVEN
WKYLLAGLVF QYIHGLAARG VHYLHRPGPT LQDLGFFLLP ELGQERAYIS ESLFTVIFLS
FVLWTFHPFI FKSKKIYTVL IWCRVLAFLC ASQFLRIVTF YSTQLPGPNY HCREGSPLAT
LPHPKSVAEV LLINFPHGVI YGCGDLIFSS HMIFTLVFVN TYQRYGTRRC IKQLGWTLIV
IQSLLIVASR KHYTVDVVVA WYTVNLVVFF VEKKLQELPD RTAATLLLPL STKDNKDGRN
KEENHKLLNG NSVDPSDWRQ RTQSNGKILE DGHAHHADST KNGA
//
