ID A0A1S2XPM4_CICAR Unreviewed; 462 AA.
AC A0A1S2XPM4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Probable amino acid permease 7 {ECO:0000313|RefSeq:XP_004491552.1};
GN Name=LOC101498232 {ECO:0000313|RefSeq:XP_004491552.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004491552.1};
RN [1] {ECO:0000313|RefSeq:XP_004491552.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004491552.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Carrier protein involved in proton-driven auxin influx.
CC Mediates the formation of auxin gradient from developing leaves (site
CC of auxin biosynthesis) to tips by contributing to the loading of auxin
CC in vascular tissues and facilitating acropetal (base to tip) auxin
CC transport within inner tissues of the root apex, and basipetal (tip to
CC base) auxin transport within outer tissues of the root apex (By
CC similarity). May be involved in lateral roots and nodules formation.
CC {ECO:0000256|ARBA:ARBA00003124}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily.
CC {ECO:0000256|ARBA:ARBA00005590}.
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DR RefSeq; XP_004491552.1; XM_004491495.3.
DR STRING; 3827.A0A1S2XPM4; -.
DR PaxDb; 3827-XP_004491552-1; -.
DR GeneID; 101498232; -.
DR KEGG; cam:101498232; -.
DR eggNOG; KOG1303; Eukaryota.
DR OrthoDB; 892775at2759; -.
DR Proteomes; UP000087171; Chromosome Ca2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR48017:SF161; AMINO ACID PERMEASE 7-RELATED; 1.
DR PANTHER; PTHR48017; OS05G0424000 PROTEIN-RELATED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022970}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..456
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
SQ SEQUENCE 462 AA; 50397 MW; 74F07A56C7FA9DC4 CRC64;
MGTASSDSSD TNIPLLLTQS NPIKRTGTVW TAVAHIVTGV IGSGVLSLPW SIAQLGWLVG
PLSILLIASS TLFSAFLLCN TYRSPNPEYG PHRSASYLDV VNFNLGTGNG RLCGLLVNIC
LYGFGIAFVI TTSISLRSIQ DSICNHNNGS ETTSELADAY YMLLFGIVQI FLSQIPNLHN
INWLSVLAAI MSFAYCFIGM GLSIMQIIEN GYAKGSIEGV STSSGTQKLW LVSQALGDVS
FSYPFSTIIM EIQDTLKSPP PENQTMKKAS VISVAITTFF YLCCGSAGYA AFGNDTPGNL
LTGFGSSKLY WLLDFANVCI VVHLVGSYQV YSQPLFANAE NWFRFKFPDS EFVNNTYTLK
LPLLPAFDLS FLSLSFRTAY VASTTVIAMI FXXXXXXXGV LGSISFWPLT IYFPVEIYLS
RSETDAWTAK WVMLQTFNIF GVVFGLFTLI GCIRGIVTEK LG
//
