ID A0A1S2XRS2_CICAR Unreviewed; 645 AA.
AC A0A1S2XRS2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DNA-binding protein SMUBP-2 {ECO:0000313|RefSeq:XP_004493524.1, ECO:0000313|RefSeq:XP_027188734.1};
GN Name=LOC101489598 {ECO:0000313|RefSeq:XP_004493524.1,
GN ECO:0000313|RefSeq:XP_027188734.1, ECO:0000313|RefSeq:XP_027188735.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004493524.1};
RN [1] {ECO:0000313|RefSeq:XP_004493524.1, ECO:0000313|RefSeq:XP_027188734.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004493524.1,
RC ECO:0000313|RefSeq:XP_027188734.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
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DR RefSeq; XP_004493524.1; XM_004493467.3.
DR RefSeq; XP_027188734.1; XM_027332933.1.
DR RefSeq; XP_027188735.1; XM_027332934.1.
DR STRING; 3827.A0A1S2XRS2; -.
DR PaxDb; 3827-XP_004493524-1; -.
DR GeneID; 101489598; -.
DR KEGG; cam:101489598; -.
DR eggNOG; KOG1803; Eukaryota.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000087171; Chromosome Ca3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd18044; DEXXQc_SMUBP2; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 2.40.30.270; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR004483; SMUBP-2/Hcs1-like.
DR InterPro; IPR048761; SMUBP-2_HCS1_1B.
DR NCBIfam; TIGR00376; IGHMBP2 family helicase; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF21138; SMUBP-2_HCS1_1B; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000313|RefSeq:XP_004493524.1,
KW ECO:0000313|RefSeq:XP_027188734.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022728};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 191..442
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|SMART:SM00487"
FT DOMAIN 209..431
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 296..332
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 645 AA; 71419 MW; FE13F8D993A4A890 CRC64;
MEKGATKKKP LSLEQFISIT TPLLDLEKEA EITSSIATGA SRNLDSAQKR GSTILNLKCV
DVQSGLMGKS LIEFQSTKGD VLPAHKFGTH DVVVLKLNKA DLGSPALGQG VVYRLKDSSI
TVAFDDIPED GLNSPLRLEK VANEVTYRRM KDALIQLSKG VQKGPASDLI PVLFGERQPT
VSKKDVSFTL FNRNLDHSQK DAISKALSSK NVFLLHGPPG TGKTTTVVEI ILQEVKRGSK
ILVCAASNIA VDNIVERVVP HRVKLVRIGH PARLLPQVLD SALDAQVLRG DNSGLANDIR
KEMKVLNGKL LKTKEKNTRR DIQKELRSLS REERKRQQLA VTDVIKTSDV ILTTLIGASS
KKLDHTSFDL VIIDEAAQAL EVACWIPLLK GSRCILAGDH LQLPPTIQSV EAEKKGLGRT
LFERLAELYE DEVTSMLTVQ YRMHQLIMDW SSKELYNSKV KAHASVAAHM LYDLENVKRT
SSTEPNLLLI DTAGCDMEEK KDEEDSTLNE GESEVAMAHA KRLVQSGVLP SDIGIITPYA
AQVVLLKMLK NKENSLKDIE ISTVDGFQGR EKEAIIISMV RSNSKKEVGF LSDRRRMNVA
VTRARRQCCI VCDTETVSSD GFLKRLVEYF EEHGEYQSAS EYQNE
//
