ID A0A1S2XS96_CICAR Unreviewed; 358 AA.
AC A0A1S2XS96;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366041};
GN Name=LOC101506603 {ECO:0000313|RefSeq:XP_004493752.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004493752.1};
RN [1] {ECO:0000313|RefSeq:XP_004493752.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004493752.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC magnesium. {ECO:0000256|RuleBase:RU366041}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU366041}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU366041}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000256|ARBA:ARBA00007535,
CC ECO:0000256|RuleBase:RU366041}.
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DR RefSeq; XP_004493752.1; XM_004493695.3.
DR AlphaFoldDB; A0A1S2XS96; -.
DR GeneID; 101506603; -.
DR OrthoDB; 73031at2759; -.
DR Proteomes; UP000087171; Chromosome Ca3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF46; PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366041};
KW Magnesium {ECO:0000256|RuleBase:RU366041};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366041};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366041};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366041}; Transport {ECO:0000256|RuleBase:RU366041}.
FT TRANSMEM 293..314
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT TRANSMEM 326..350
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT REGION 202..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 40455 MW; 9B02235072AA342F CRC64;
MAVSGSETEL RVQATMIKTT ISRSWVLLDR DGRDTVLDVD KYAIMRLVEI NARDLRILDP
LLSYPSTILG REKVIVLNLE HIKAVITADE VLVRDPMDDD VIPVVEELRR RLPLKVSFGG
QDQGEEESSI GEQNEFPFEF RALEVVLEAI CSFLDARTRE LETTAYPALD ELTSKIREEL
ENLLDDDDDM AELYLSRKLG VSSSPSSSSS GPNWHQNSPN QGSKIHKSSR GSATTLQEEN
DVEELEMLLE AYFVQIDGTL NKLTTLREYI DDTEDYINIQ LDNHRNKLIQ LELFLSSGTV
CLSIYSLVVA IFGMNIPYTW REDHGYVFKW VVIFTGMACS SVFLSVVSYA RRKGLVGS
//
