ID A0A1S2Y0A5_CICAR Unreviewed; 458 AA.
AC A0A1S2Y0A5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=COBW domain-containing protein 1-like {ECO:0000313|RefSeq:XP_004497313.1};
GN Name=LOC101496864 {ECO:0000313|RefSeq:XP_004497313.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004497313.1};
RN [1] {ECO:0000313|RefSeq:XP_004497313.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004497313.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR RefSeq; XP_004497313.1; XM_004497256.3.
DR AlphaFoldDB; A0A1S2Y0A5; -.
DR STRING; 3827.A0A1S2Y0A5; -.
DR PaxDb; 3827-XP_004497313-1; -.
DR GeneID; 101496864; -.
DR KEGG; cam:101496864; -.
DR eggNOG; KOG2743; Eukaryota.
DR OrthoDB; 1010489at2759; -.
DR Proteomes; UP000087171; Chromosome Ca4.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171}.
FT DOMAIN 363..457
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 67..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 50843 MW; 7A70FE1E81E227C1 CRC64;
MACFAAAELA SSFFGTASRN PKHFTLLCTN NTRIITTPRT KTHFQPLNSS SFSRIFRNSS
INKLSRRFSV SSSTSSPPQT DSSDEVSTVI PPDNRIPATI ITGFLGSGKT TLLNHILTAE
HGKRIAVIEN EFGEIDIDGS LVAAKTAGAE DIMLLNNGCL CCTVRGDLVR MISELVTSKK
GKFDHIVIET TGLANPAPII QTFYAEDNIF NEVKLDGVVT LVDAKHAGLH LDEVKPKGVV
NEAVEQIAYA DRIIVNKTDL VGESDIASLV QRIRKINSLA NLKRTEYGKV NLDYVLGIGG
FDLERIESAV NDEGSKEEDH AHSHDHDHEH EHHHHDHHHH HHDDSHDHKH DHHSHDHSHD
PGVSSVSIVC EGNLDLEKAN MWLGTLLMER SEDIYRMKGL LSVQGMDERF VFQGVHDIFQ
GSPERLWGPD EPRTNKIVFI GKNLEAEELE KGFKACLL
//
