ID A0A1S2Y485_CICAR Unreviewed; 548 AA.
AC A0A1S2Y485;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Nucleobase-ascorbate transporter 3 {ECO:0000313|RefSeq:XP_004499100.1};
GN Name=LOC101493208 {ECO:0000313|RefSeq:XP_004499100.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004499100.1};
RN [1] {ECO:0000313|RefSeq:XP_004499100.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004499100.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR RefSeq; XP_004499100.1; XM_004499043.3.
DR AlphaFoldDB; A0A1S2Y485; -.
DR STRING; 3827.A0A1S2Y485; -.
DR PaxDb; 3827-XP_004499100-1; -.
DR GeneID; 101493208; -.
DR KEGG; cam:101493208; -.
DR eggNOG; KOG1292; Eukaryota.
DR OrthoDB; 345287at2759; -.
DR Proteomes; UP000087171; Chromosome Ca4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF29; NUCLEOBASE-ASCORBATE TRANSPORTER 3; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 60069 MW; 9910F9F432920CF0 CRC64;
MGETDHHHAP PSAQAPPPGP PPQNLGLSRG PTWTPAEQLL QLHYCIHSNP SWPEALLLGF
QHYIVMLGTT VLIASNLVPQ MGGNHGDKAR VIQTLLFMSG VNTLLQSWFG SRLPVVMGGS
LAFVLPVMSI INDYNDQSFS SEHQRFTYTM RTIQGSLIVS SFINIFLGYS RTWGNLTRLF
SPIVIVPVVC VVGLGLFARG FPMLADCVQI GLPMLILLVI TQQYLKRLHP TAHHVLERFA
LLICIGIVWA FAAILTVAGA YNTSKQQTQV SCRTDRSYLL SSAPWIKFPY PFQWGTPIFK
ASHVFGMMGA ALVSSAESTG TFFAAARLSG ATPPPAHVLT RSIGLQGLSM LLEGIFGSIV
GTTASVENVG LLGLTHIGSR RVVQISCAFM IFFSIFGKFG AFFASIPLPI FAAIYCVLFG
IVAAVGISFI QFTNNNSIRN IYVFGLTLFL GISIPQYFIM NTSPDGHGPV RTNGGWFNDI
LNTIFSSPPT VAIIVGTVLD NTLEAKQTAV DRGMQWWAPF QNKKGDVRND EFYRFPLRLT
EYIPTRFL
//
