ID A0A1S2Y9J5_CICAR Unreviewed; 887 AA.
AC A0A1S2Y9J5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Coatomer subunit gamma {ECO:0000256|PIRNR:PIRNR037093};
GN Name=LOC101495461 {ECO:0000313|RefSeq:XP_004500815.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004500815.1};
RN [1] {ECO:0000313|RefSeq:XP_004500815.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004500815.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR037093}.
CC -!- SUBUNIT: Oligomeric complex. {ECO:0000256|PIRNR:PIRNR037093}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037093}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR037093}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR037093};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR037093}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR037093}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR037093}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR037093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the COPG family. {ECO:0000256|ARBA:ARBA00010720,
CC ECO:0000256|PIRNR:PIRNR037093}.
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DR RefSeq; XP_004500815.1; XM_004500758.3.
DR AlphaFoldDB; A0A1S2Y9J5; -.
DR STRING; 3827.A0A1S2Y9J5; -.
DR PaxDb; 3827-XP_004500815-1; -.
DR GeneID; 101495461; -.
DR KEGG; cam:101495461; -.
DR eggNOG; KOG1078; Eukaryota.
DR OrthoDB; 5260816at2759; -.
DR Proteomes; UP000087171; Chromosome Ca5.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1480; Coatomer, gamma subunit, appendage domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR032154; Coatomer_g_Cpla.
DR InterPro; IPR017106; Coatomer_gsu.
DR InterPro; IPR013040; Coatomer_gsu_app_Ig-like_dom.
DR InterPro; IPR037067; Coatomer_gsu_app_sf.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10261; COATOMER SUBUNIT GAMMA; 1.
DR PANTHER; PTHR10261:SF6; COATOMER SUBUNIT GAMMA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF16381; Coatomer_g_Cpla; 1.
DR Pfam; PF08752; COP-gamma_platf; 1.
DR PIRSF; PIRSF037093; Coatomer_gamma_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR037093};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW ECO:0000256|PIRNR:PIRNR037093};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037093};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037093}.
FT DOMAIN 27..540
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 622..767
FT /note="Coatomer gamma subunit appendage Ig-like subdomain"
FT /evidence="ECO:0000259|Pfam:PF08752"
FT DOMAIN 770..884
FT /note="Coatomer subunit gamma C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16381"
FT REGION 588..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 98635 MW; 83F0E5FEF42314B3 CRC64;
MAQQLVKKDD DRDDEAEYSP FMGIEKGAVL QEARVFNDPQ LDARRCSQVI TKLLYLLNQG
ETFTKTEATE VFFAVTKLFQ SRDMGLRRMV YLMIKEISPS ADEVIIVTSS LMKDMNSKID
MYRANAIRVL CRITDGTLLA QIERYLKQAI VDKNPVVASA ALVSGIHLLQ TNPEIVKRWS
NEVQEAVQSR AALVQFHALG LLHQIRQNDR LAVSKLVTSL TKGTVRSPLA QCLLIRYTSQ
VIRESGNNTQ SGDRPFYDYL ESCLRHKSEM VIFEAARAIT ELNGVTSREL TPAITVLQLF
LSSSKPVLRF AAVRTLNKVA MTHPTSVTNC NIDMESLISD QNRSIATLAI TTLLKTGNES
SVDRLMKQIT NFMSDIADEF KIVVVEAIRS LCQKFPLKYR SLMNFLSNIL REEGGFEYKK
AIVDSIVILI REIPDAKETG LLHLCEFIED CEFTYLSTQI LHFLGIEGPK TSDPSRYIRF
IYNRVHLENA TVRAGAVSTL AKFGAAVDEL KPRIFVLLRR CLFDSDDEVR DRATLYLNTL
GGDGSVVETD KAVKDFLFGP FDIPLVNLET SLKNYEPSEE AFDIDSVPKE VKSQSLAEKK
APGKKPTGLG APPSGPPSTA DAYQKILSSI PEFANFGNLF KSSAPVELTE AETEYAVNVV
KHIFDRHVVF QYNCTNTIPE QLLENVIVIV DSSEADEFAE VFSKPLKSLP YDSPGQIFVA
FEKPEGAPTL GKFSNVLKFI VREVDPTTGE AEDDGVEDEY QLEDLEIVSA DYTLKVAVSN
FRNAWESMGP DCERVDEYGL GPRESLAEAV NTVINLLGLQ PCEGTEVVPP NSRSHTCLLS
GVYIGNVKVL VRLSFGLDGP KDVAMKLTVR SDDETVSDAI HEIVASG
//
